Literature summary for 2.3.1.95 extracted from

Jeong, Y.J.; Woo, S.G.; An, C.H.; Jeong, H.J.; Hong, Y.S.; Kim, Y.M.; Ryu, Y.B.; Rho, M.C.; Lee, W.S.; Kim, C.Y.
Metabolic engineering for resveratrol derivative biosynthesis in Escherichia coli (2015), Mol. Cells, 38, 318-326.

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Application

Application	Comment	Organism
synthesis	synthesis of resveratrol from 4-coumaric acid can be achieved after codon-optimization for expression in Escherichia coli and coexpression with cinnamate/4-coumarate:coenzyme A ligase. Additional expression of resvertrol O-methyltransferase results in production of pinostilbene and pterostilbene	Rheum palmatum
synthesis	synthesis of resveratrol from 4-coumaric acid upon coexpression with cinnamate/4-coumarate:coenzyme A ligase in Escherichia coli	Arachis hypogaea

Cloned(Commentary)

Cloned (Comment)	Organism
-	Rheum palmatum

Molecular Weight [Da]

Molecular Weight [Da]	Molecular Weight Maximum [Da]	Comment	Organism
42800	-	x * 42800, calculated	Rheum palmatum

Organism

Organism	UniProt	Comment	Textmining
Arachis hypogaea	K7XD27	-	-
Rheum palmatum	K7X0B4	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
3 malonyl-CoA + 4-coumaroyl-CoA	-	Arachis hypogaea	4 CoA + resveratrol + 4 CO2	out of three enzymes tested, only stilbene synthase from Arachis hypogaea is able to produce resveratrol from 4-coumaric acid	?
additional information	no substrates: caffeic acid, ferulic acid, and cinnamic acid	Rheum palmatum	?	-	?

Subunits

Subunits	Comment	Organism
?	x * 42800, calculated	Rheum palmatum

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Release 2023.1 (January 2023)