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Literature summary for 2.3.1.9 extracted from

  • Jin, H.; Song, Z.; Nikolau, B.J.
    Reverse genetic characterization of two paralogous acetoacetyl CoA thiolase genes in Arabidopsis reveals their importance in plant growth and development (2012), Plant J., 70, 1015-1032.
    View publication on PubMed

Organism

Organism UniProt Comment Textmining
Arabidopsis thaliana Q8S4Y1 cytosolic acetoacetyl-CoA thiolase 1
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Arabidopsis thaliana Q9FIK7 cytosolic acetoacetyl-CoA thiolase 2
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Source Tissue

Source Tissue Comment Organism Textmining
anther isoform AACT! is highly expressed in root tips, young leaf, top stem and anther Arabidopsis thaliana
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leaf isoform AACT! is highly expressed in root tips, young leaf, top stem and anther Arabidopsis thaliana
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root isoform AACT! is highly expressed in root tips, young leaf, top stem and anther Arabidopsis thaliana
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stem isoform AACT! is highly expressed in root tips, young leaf, top stem and anther Arabidopsis thaliana
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vascular system isoform AACT! is primarily expressed in the vascular system Arabidopsis thaliana
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Synonyms

Synonyms Comment Organism
AACT1
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Arabidopsis thaliana
AACT2
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Arabidopsis thaliana
cytosolic acetoacetyl-CoA thiolase 1
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Arabidopsis thaliana
cytosolic acetoacetyl-CoA thiolase 2
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Arabidopsis thaliana

General Information

General Information Comment Organism
physiological function isoform AACT2 function is required for embryogenesis and for normal male gamete transmission. RNAi lines that express reduced levels of isoform AACT2 show pleiotropic phenotypes, including reduced apical dominance, elongated life span and flowering duration, sterility, dwarfing, reduced seed yield and shorter root length. The reduced stature is caused by a reduction in cell size and fewer cells, and male sterility is caused by loss of the pollen coat and premature degeneration of the tapetal cells. The roots of AACT2 RNAi plants show quantitative and qualitative alterations in phytosterol profiles. These phenotypes and biochemical alterations are reversed when AACT2 RNAi plants are grown in the presence of mevalonate Arabidopsis thaliana
physiological function plants lacking isoform AACT1 function are completely viable and show no apparent growth phenotypes Arabidopsis thaliana