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Literature summary for 2.3.1.86 extracted from

  • Runguphan, W.; Keasling, J.
    Metabolic engineering of Saccharomyces cerevisiae for production of fatty acid-derived biofuels and chemicals (2014), Metab. Eng., 21, 103-113 .
    View publication on PubMedView publication on EuropePMC

Application

Application Comment Organism
biofuel production Saccharomyces cerevisiae is engineered to produce fatty acid-derived biofuels and chemicals from simple sugars. All three primary genes involved in fatty acid biosynthesis, namely ACC1, FAS1 and FAS2 are overexpressed. Combining this metabolic engineering strategy with terminal converting enzymes (diacylglycerol-acyltransferase,fatty acyl-CoA thioesterase,fatty acyl-CoA reductase, and wax ester synthase for TAG,fatty acid, fatty alcohol and FAEE production, respectively) improves the production levels of all biofuel molecules and chemicals, Saccharomyces cerevisiae provides a compelling platform for a scalable, controllable and economic route to biofuel molecules and chemicals Saccharomyces cerevisiae

Organism

Organism UniProt Comment Textmining
Saccharomyces cerevisiae
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Saccharomyces cerevisiae BY4742
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Synonyms

Synonyms Comment Organism
FAS1
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Saccharomyces cerevisiae
fas2
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Saccharomyces cerevisiae