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Literature summary for 2.3.1.85 extracted from

  • Duckett, S.K.; Pratt, S.L.; Pavan, E.
    Corn oil or corn grain supplementation to steers grazing endophyte-free tall fescue. II. Effects on subcutaneous fatty acid content and lipogenic gene expression (2009), J. Anim. Sci., 87, 1120-1128.
    View publication on PubMed
Search for more literature for 2.3.1.85

Organism

Organism UniProt Comment Textmining
Bos taurus
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-
-

Source Tissue

Source Tissue Comment Organism Textmining
subcutaneous adipose tissue
-
 Bos taurus
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
acetyl-CoA + 7 malonyl-CoA + 14 NADPH + 14 H+
-
 Bos taurus palmitate + 8 CoA + 7 CO2 + 14 NADP+ + 6 H2O
-
 ?

Synonyms

Synonyms Comment Organism
FASN
-
 Bos taurus
fatty acid synthase
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 Bos taurus

Cofactor

Cofactor Comment Organism Structure
NADPH
-
 Bos taurus

Expression

Organism Comment Expression
Bos taurus relative FASN mRNA expression is upregulated by 9 and 5fold, respectively, for high-concentrate diet (85% concentrate: 15% roughage) and diet on endophyte-free tall fescue pastures with corn grain supplement compared with pasture diet, grain feeding upregulates FASN mRNA expression up

General Information

General Information Comment Organism
physiological function fatty acid synthase is a key enzyme regulating de novo fatty acid synthesis Bos taurus