Inhibitors | Comment | Organism | Structure |
---|---|---|---|
galangin | poor inhibition | Gallus gallus | |
kaempferol | 50% inhibition at 0.00298 mg/ml | Gallus gallus | |
additional information | inhibition by extract from rhizome of Alpinia officinarum, i.e. galangal. Inhibition consists of both reversible inhibition with an IC50-value of 0.0017 mg dried extract per ml, and biphasic slow-binding inactivation | Gallus gallus | |
quercetin | 50% inhibition at 0.0024 mg/ml, mixed type inhibition for substrate NADPH, competitive with substrate acetyl-CoA, noncompetitive with malonyl-CoA | Gallus gallus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Gallus gallus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Gallus gallus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
acetyl-CoA + 7 malonyl-CoA + 14 NADPH + 14 H+ | - |
Gallus gallus | palmitate + 8 CoA + 7 CO2 + 14 NADP+ + 6 H2O | - |
? |
Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
---|---|---|---|---|---|
0.00183 | - |
quercetin | substrate NADPH, pH 7.0, 37°C | Gallus gallus | |
0.00301 | - |
quercetin | substrate acetyl-CoA, pH 7.0, 37°C | Gallus gallus |