Inhibitors | Comment | Organism | Structure |
---|---|---|---|
(2S)-3-[(2S)-2-([[(1S)-2-amino-1-phenylethyl]amino]methyl)pyrrolidin-1-yl]-2-([(2S)-2-phenyl-2-[(3-phenylbutyl)amino]ethyl]amino)propan-1-ol | robust enzymatic inhibitor in vitro, in combination with amikacin potentiates the inhibition of growth of resistant bacteria in culture, and improves survival when used as treatment of Galleria mellonella infected with aac(6')-Ib-harboring Klebsiella pneumoniae and Acinetobacter baumannii strains | Acinetobacter baumannii | |
(2S)-3-[(2S)-2-([[(1S)-2-amino-1-phenylethyl]amino]methyl)pyrrolidin-1-yl]-2-([(2S)-2-phenyl-2-[(3-phenylbutyl)amino]ethyl]amino)propan-1-ol | robust enzymatic inhibitor in vitro, in combination with amikacin potentiates the inhibition of growth of resistant bacteria in culture, and improves survival when used as treatment of Galleria mellonella infected with aac(6')-Ib-harboring Klebsiella pneumoniae and Acinetobacter baumannii strains | Klebsiella pneumoniae |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Acinetobacter baumannii | - |
- |
- |
Acinetobacter baumannii A155 | - |
- |
- |
Klebsiella pneumoniae | - |
- |
- |
Klebsiella pneumoniae JHCK1 | - |
- |
- |
Synonyms | Comment | Organism |
---|---|---|
6'-N-acetyltransferase type Ib | - |
Klebsiella pneumoniae |
6'-N-acetyltransferase type Ib | - |
Acinetobacter baumannii |
AAC(6')-Ib | - |
Klebsiella pneumoniae |
AAC(6')-Ib | - |
Acinetobacter baumannii |