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Literature summary for 2.3.1.81 extracted from

  • Ung, K.; Alsarraf, H.; Olieric, V.; Kremer, L.; Blaise, M.
    Crystal structure of the aminoglycosides N-acetyltransferase Eis2 from Mycobacteriumxa0abscessus (2019), FEBS J., 286, 4342-4355 .
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
expression in Escherichia coli Mycobacteroides abscessus

Crystallization (Commentary)

Crystallization (Comment) Organism
structures of apo-enzyme and in complex with acetyl-CoA Mycobacteroides abscessus

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.0362
-
acetyl-CoA 25°C, pH not specified in the publication Mycobacteroides abscessus

Organism

Organism UniProt Comment Textmining
Mycobacteroides abscessus B1MKV6
-
-
Mycobacteroides abscessus DSM 44196 B1MKV6
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
acetyl-CoA + kanamycin
-
Mycobacteroides abscessus CoA + N3'-acetylkanamycin
-
?
acetyl-CoA + kanamycin
-
Mycobacteroides abscessus DSM 44196 CoA + N3'-acetylkanamycin
-
?

Synonyms

Synonyms Comment Organism
Eis2
-
Mycobacteroides abscessus
Enhanced in Intracellular Survival
-
Mycobacteroides abscessus

Turnover Number [1/s]

Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
2.2
-
acetyl-CoA 25°C, pH not specified in the publication Mycobacteroides abscessus