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Literature summary for 2.3.1.80 extracted from

  • Duffel, M.W.; Jakoby, W.B.
    Cysteine S-conjugate N-acetyltransferase (1985), Methods Enzymol., 113, 516-521.
    View publication on PubMed
Search for more literature for 2.3.1.80

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
additional information
-
 additional information substitution of oxygen for sulfur as in O-benzyl-L-serine, greatly increases the apparent Km, with only slight decrease in maximal velocity Rattus norvegicus
0.026
-
 S-acetyl-CoA
-
 Rattus norvegicus
0.063
-
 S-butyl-L-cysteine
-
 Rattus norvegicus
0.14
-
 S-Benzyl-L-cysteine
-
 Rattus norvegicus
0.67
-
 S-propyl-L-cysteine
-
 Rattus norvegicus
2.6
-
 O-benzyl-L-serine
-
 Rattus norvegicus
7.1
-
 S-ethyl-L-cysteine
-
 Rattus norvegicus

Localization

Localization Comment Organism GeneOntology No. Textmining
microsome
-
 Rattus norvegicus
-
-

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Purification (Commentary)

Purification (Comment) Organism
partial Rattus norvegicus

Source Tissue

Source Tissue Comment Organism Textmining
kidney
-
 Rattus norvegicus
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
0.394
-
-
 Rattus norvegicus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
acetyl-CoA + O-benzyl-L-serine
-
 Rattus norvegicus CoA + N-acetyl-O-benzyl-L-cysteine
-
 ?
acetyl-CoA + S-benzyl-L-cysteine best substrate Rattus norvegicus CoA + N-acetyl-S-benzyl-L-cysteine
-
 ?
acetyl-CoA + S-butyl-L-cysteine
-
 Rattus norvegicus CoA + N-acetyl-S-butyl-L-cysteine
-
 ?
acetyl-CoA + S-ethyl-L-cysteine
-
 Rattus norvegicus CoA + N-acetyl-S-ethyl-L-cysteine
-
 ?
acetyl-CoA + S-propyl-L-cysteine
-
 Rattus norvegicus CoA + N-acetyl-S-propyl-L-cysteine
-
 ?
additional information no substrate: aniline, o-aminobenzoate, D-cysteine, L-methionine, L-leucine, L-phenylalanine, L-glutamate Rattus norvegicus ?
-
 ?

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
37
-
 assay at Rattus norvegicus

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
6.8 7
-
 Rattus norvegicus