Literature summary for 2.3.1.78 extracted from

Reynertson, R.; Campbell, P.; Ford, J.D.; Jacobsson, I.; Roden, L.; Thompson, J.N.
New oligosaccharides from heparin and heparan sulfate and their use as substrates for heparin-degrading enzymes (1983), J. Biol. Chem., 258, 7449-7459.

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Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
acetyl-CoA + heparan sulfate alpha-D-glucosaminide	Homo sapiens	-	CoA + heparan sulfate N-acetyl-alpha-D-glucosaminide	-	?

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
skin fibroblast	deficiency on fibroblasts from patients with Sanfillippo syndrome type C	Homo sapiens	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
acetyl-CoA + glucosamine-L-iduronic acid-D-glucosamine	reduced with NaBH4	Homo sapiens	?	-	?
acetyl-CoA + heparan sulfate alpha-D-glucosaminide	-	Homo sapiens	CoA + heparan sulfate N-acetyl-alpha-D-glucosaminide	-	?

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Release 2023.1 (January 2023)