Literature summary for 2.3.1.65 extracted from

Shonsey, E.M.; Eliuk, S.M.; Johnson, M.S.; Barnes, S.; Falany, C.N.; Darley-Usmar, V.M.; Renfrow, M.B.
Inactivation of human liver bile acid CoA:amino acid N-acyltransferase by the electrophilic lipid, 4-hydroxynonenal (2008), J. Lipid Res., 49, 282-294.

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Cloned(Commentary)

Cloned (Comment)	Organism
expression in Escherichia coli	Homo sapiens

Inhibitors

Inhibitors	Comment	Organism	Structure
4-hydroxynonenal	inactivated by 4HNE in a dose-dependent manner. The active-site His (His362) dose-dependently forms a 4-hydroxynonenal adduct, contributing to loss of activity	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Purification (Commentary)

Purification (Comment)	Organism
-	Homo sapiens

Source Tissue

Source Tissue	Comment	Organism	Textmining
liver	-	Homo sapiens	-

Synonyms

Synonyms	Comment	Organism
BAT	-	Homo sapiens

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Release 2023.1 (January 2023)