Activating Compound | Comment | Organism | Structure |
---|---|---|---|
Pectin | dietary pectin relative to cellulose activates, especially the glycine-dependent activity | Rattus norvegicus |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.8 | 2.5 | taurine | - |
Rattus norvegicus | |
0.83 | - |
taurine | rats fed with cellulose | Rattus norvegicus | |
1.02 | - |
taurine | rats fed with pectin | Rattus norvegicus | |
35 | 40 | glycine | - |
Rattus norvegicus | |
38 | - |
glycine | rats fed with cellulose | Rattus norvegicus | |
40 | - |
glycine | rats fed with pectin | Rattus norvegicus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
additional information | in the post-mitochondrial fraction of liver homogenates | Rattus norvegicus | - |
- |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
choloyl-CoA + taurine | Rattus norvegicus | taurine conjugates predominate in rat bile at normal hepatocellular concentrations of glycine and taurine | CoA + taurocholate | - |
? | |
choloyl-CoA + taurine | Rattus norvegicus | bile acid conjugation | CoA + taurocholate | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
male Wistar rats, 4 weeks old | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
choloyl-CoA + glycine | produces taurine- but little glycine-conjugated bile acid at physiological concentrations of glycine and taurine, dietary manipulations modify the glycine:taurine ratio | Rattus norvegicus | CoA + glycocholate | - |
? | |
choloyl-CoA + taurine | produces taurine- but little glycine-conjugated bile acid at physiological concentrations of glycine and taurine, dietary manipulations modify the hepatic taurine concentration and glycine:taurine ratio | Rattus norvegicus | CoA + taurocholate | - |
? | |
choloyl-CoA + taurine | taurine conjugates predominate in rat bile at normal hepatocellular concentrations of glycine and taurine | Rattus norvegicus | CoA + taurocholate | - |
? | |
choloyl-CoA + taurine | bile acid conjugation | Rattus norvegicus | CoA + taurocholate | - |
? |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
assay at | Rattus norvegicus |