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Literature summary for 2.3.1.60 extracted from

  • Evangelisti, E.; Yunusov, T.; Shenhav, L.; Schornack, S.
    N-acetyltransferase AAC(3)-I confers gentamicin resistance to Phytophthora palmivora and Phytophthora infestans (2019), BMC Microbiol., 19, 265 .
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.3.1.60

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Phytophthora palmivora strain LILI and Phytophthora infestans strain 88069 Pseudomonas aeruginosa

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
acetyl-CoA + astromicin Pseudomonas aeruginosa
-
 CoA + N3-acetylastromicin
-
 ?
acetyl-CoA + gentamicin Pseudomonas aeruginosa
-
 CoA + N3-acetylgentamicin
-
 ?
acetyl-CoA + sisomicin Pseudomonas aeruginosa
-
 CoA + N3-acetylsisomicin
-
 ?

Organism

Organism UniProt Comment Textmining
Pseudomonas aeruginosa
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
acetyl-CoA + astromicin
-
 Pseudomonas aeruginosa CoA + N3-acetylastromicin
-
 ?
acetyl-CoA + gentamicin
-
 Pseudomonas aeruginosa CoA + N3-acetylgentamicin
-
 ?
acetyl-CoA + sisomicin
-
 Pseudomonas aeruginosa CoA + N3-acetylsisomicin
-
 ?

Synonyms

Synonyms Comment Organism
AAC(3)-I
-
 Pseudomonas aeruginosa
aacC1
-
 Pseudomonas aeruginosa
aminoglycoside 3-Nacetyltransferase I
-
 Pseudomonas aeruginosa

General Information

General Information Comment Organism
physiological function the enzyme confers gentamicin resistance but retains geneticin susceptibility Pseudomonas aeruginosa