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Literature summary for 2.3.1.6 extracted from

  • Dey, S.; Ray, K.
    Cholinergic activity is essential for maintaining the anterograde transport of choline acetyltransferase in Drosophila (2018), Sci. Rep., 8, 8028 .
    View publication on PubMedView publication on EuropePMC

Organism

Organism UniProt Comment Textmining
Drosophila melanogaster P07668
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Source Tissue

Source Tissue Comment Organism Textmining
neuron sensory neuron Drosophila melanogaster
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General Information

General Information Comment Organism
physiological function direct interaction between the kinesin-2 motor and ChAT for brief duration induces the episodic flow towards synapse, and synaptic activity is essential for this interaction. Blocking the acetylcholine synthesis through the HC3 treatment, and activation of the post synaptic neurons through the inhibition of actylcholine receptors by BTX, respectively, reduce the axonal entry and disrupt the episodic nature of ChAT transport within a short time Drosophila melanogaster