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Literature summary for 2.3.1.6 extracted from

  • Contestabile, A.; Ciani, E.; Contestabile, A.
    The place of choline acetyltransferase activity measurement in the "cholinergic hypothesis" of neurodegenerative diseases (2008), Neurochem. Res., 33, 318-327.
    View publication on PubMed

Organism

Organism UniProt Comment Textmining
Homo sapiens
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-
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Mus musculus
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-
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Source Tissue

Source Tissue Comment Organism Textmining
brain
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Mus musculus
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corpus striatum ChAT activity is higher in Ts65Dn mice at both 19 and 24 months of age compared to normogenic animals Mus musculus
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hippocampus ChAT activity is increased at 10 and 12 months of age in the hippocampus of Ts65Dn mice compared to normogenic animals Mus musculus
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hippocampus increased ChAT activity in some brain regions, notably the hippocampus, of patients diagnosed with mild cognitive impairment Homo sapiens
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occipital lobe no significant differences of ChAT activity are measured at both 19 and 24 months of age between Ts65Dn mice and normogenic animals Mus musculus
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olfactory bulb
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Mus musculus
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olfactory cortex no significant differences of ChAT activity are measured at both 19 and 24 months of age between Ts65Dn mice and normogenic animals Mus musculus
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Synonyms

Synonyms Comment Organism
ChAT
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Mus musculus
ChAT
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Homo sapiens