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Literature summary for 2.3.1.57 extracted from

  • Sun, H.; Liu, B.; Wang, W.; Jiang, G.S.; Li, W.; Yang, Y.P.; Xu, C.X.; Yan, Y.F.; Liu, X.X.
    Adenovirus-mediated expression of spermidine/spermine N1-acetyltransferase gene induces S-phase arrest in human colorectal cancer cells (2008), Oncol. Rep., 20, 1229-1235.
    View publication on PubMed
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Cloned(Commentary)

Cloned (Comment) Organism
expression of SSAT in HT-29 cells and LoVo cells, two colorectal cancer cell lines, using an adenoviral vector, recombinant enzyme expression causes arrest of cell cycle and cell growth in the S-phase Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Homo sapiens SSAT expression causes arrest of cell cycle and cell growth in the S-phase in transfected cells through a mechanism involving the suppression of cyclin A and E2F1-expression, overview ?
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 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens
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Source Tissue

Source Tissue Comment Organism Textmining

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information SSAT expression causes arrest of cell cycle and cell growth in the S-phase in transfected cells through a mechanism involving the suppression of cyclin A and E2F1-expression, overview Homo sapiens ?
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 ?

Synonyms

Synonyms Comment Organism
spermidine/spermine N1-acetyltransferase
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 Homo sapiens
SSAT
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 Homo sapiens

General Information

General Information Comment Organism
metabolism SSAT is a key enzyme of polyamine catabolism Homo sapiens