Literature summary for 2.3.1.57 extracted from

Allen, W.L.; McLean, E.G.; Boyer, J.; McCulla, A.; Wilson, P.M.; Coyle, V.; Longley, D.B.; Casero, R.A.; Johnston, P.G.
The role of spermidine/spermine N1-acetyltransferase in determining response to chemotherapeutic agents in colorectal cancer cells (2007), Mol. Cancer Ther., 6, 128-137.

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Application

Application	Comment	Organism
medicine	the enzyme may be an important target for therapeutic intervention in colorectal cancer	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
HCT-116 cell	the enzyme is inducible in response to 5-fluorouracil or oxaliplatin in parental and drugresistant HCT116 cell lines	Homo sapiens	-

Synonyms

Synonyms	Comment	Organism
spermidine/spermine N1-acetyltransferase	-	Homo sapiens

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Release 2023.1 (January 2023)