Any feedback?
Please rate this page
(literature.php)
(0/150)

BRENDA support

Literature summary for 2.3.1.51 extracted from

  • Bradley, R.M.; Marvyn, P.M.; Aristizabal Henao, J.J.; Mardian, E.B.; George, S.; Aucoin, M.G.; Stark, K.D.; Duncan, R.E.
    Acylglycerophosphate acyltransferase 4 (AGPAT4) is a mitochondrial lysophosphatidic acid acyltransferase that regulates brain phosphatidylcholine, phosphatidylethanolamine, and phosphatidylinositol levels (2015), Biochim. Biophys. Acta, 1851, 1566-1576.
    View publication on PubMed
Search for more literature for 2.3.1.51

Cloned(Commentary)

Cloned (Comment) Organism
expressed in HEK-293 or Sf9 insect cells Mus musculus

Localization

Localization Comment Organism GeneOntology No. Textmining
mitochondrion
-
 Mus musculus 5739
-
outer mitochondrial membrane
-
 Mus musculus
-
-

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
44000
-
 x * 44000, SDS-PAGE Mus musculus

Organism

Organism UniProt Comment Textmining
Mus musculus Q8K4X7
-
-

Source Tissue

Source Tissue Comment Organism Textmining
brain
-
 Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
oleoyl-CoA + 1-arachidonoyl-sn-glycerol 3-phosphate
-
 Mus musculus CoA + 1-arachidonoyl-2-oleoyl-sn-glycerol 3-phosphate
-
 ?
oleoyl-CoA + 1-oleoyl-sn-glycerol 3-phosphate
-
 Mus musculus CoA + 1,2-dioleoyl-sn-glycerol 3-phosphate
-
 ?

Subunits

Subunits Comment Organism
? x * 44000, SDS-PAGE Mus musculus

Synonyms

Synonyms Comment Organism
acyl-CoA:lysophospholipid acyltransferase
-
 Mus musculus
acylglycerophosphate acyltransferase 4
-
 Mus musculus
AGPAT4
-
 Mus musculus
LPAATdelta
-
 Mus musculus
lysophosphatidic acid acyltransferase
-
 Mus musculus

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.4
-
-
 Mus musculus

General Information

General Information Comment Organism
metabolism the enzyme specifically supports synthesis of brain phosphatidylinositol, phosphatidylcholine, and phosphatidylethanolamine Mus musculus