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Literature summary for 2.3.1.50 extracted from

  • Ziv, C.; Malitsky, S.; Othman, A.; Ben-Dor, S.; Wei, Y.; Zheng, S.; Aharoni, A.; Hornemann, T.; Vardi, A.
    Viral serine palmitoyltransferase induces metabolic switch in sphingolipid biosynthesis and is required for infection of a marine alga (2016), Proc. Natl. Acad. Sci. USA, 113, E1907-E1916 .
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.3.1.50

Inhibitors

Inhibitors Comment Organism Structure
myriocin
-
 Emiliania huxleyi
myriocin
-
 Emiliania huxleyi virus sp.

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
palmitoyl-CoA + L-serine Emiliania huxleyi virus sp.
-
 CoA + 3-dehydro-D-sphinganine + CO2
-
 ?
palmitoyl-CoA + L-serine Emiliania huxleyi virus sp. 201
-
 CoA + 3-dehydro-D-sphinganine + CO2
-
 ?
pentadecanoyl-CoA + L-serine Emiliania huxleyi
-
 ?
-
 ?
pentadecanoyl-CoA + L-serine Emiliania huxleyi CCMP374
-
 ?
-
 ?

Organism

Organism UniProt Comment Textmining
Emiliania huxleyi
-
-
-
Emiliania huxleyi CCMP374
-
-
-
Emiliania huxleyi virus sp.
-
-
-
Emiliania huxleyi virus sp. 201
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
heptadecanoyl-CoA + L-serine
-
 Emiliania huxleyi ?
-
 ?
heptadecanoyl-CoA + L-serine less than 50% activity compared to palmitoyl-CoA Emiliania huxleyi virus sp. ?
-
 ?
heptadecanoyl-CoA + L-serine less than 50% activity compared to palmitoyl-CoA Emiliania huxleyi virus sp. 201 ?
-
 ?
heptadecanoyl-CoA + L-serine
-
 Emiliania huxleyi CCMP374 ?
-
 ?
myristoyl-CoA + L-serine
-
 Emiliania huxleyi ?
-
 ?
myristoyl-CoA + L-serine less than 50% activity compared to palmitoyl-CoA Emiliania huxleyi virus sp. ?
-
 ?
myristoyl-CoA + L-serine less than 50% activity compared to palmitoyl-CoA Emiliania huxleyi virus sp. 201 ?
-
 ?
myristoyl-CoA + L-serine
-
 Emiliania huxleyi CCMP374 ?
-
 ?
palmitoyl-CoA + L-serine
-
 Emiliania huxleyi CoA + 3-dehydro-D-sphinganine + CO2
-
 ?
palmitoyl-CoA + L-serine
-
 Emiliania huxleyi virus sp. CoA + 3-dehydro-D-sphinganine + CO2
-
 ?
palmitoyl-CoA + L-serine 100% activity Emiliania huxleyi virus sp. CoA + 3-dehydro-D-sphinganine + CO2
-
 ?
palmitoyl-CoA + L-serine
-
 Emiliania huxleyi virus sp. 201 CoA + 3-dehydro-D-sphinganine + CO2
-
 ?
palmitoyl-CoA + L-serine 100% activity Emiliania huxleyi virus sp. 201 CoA + 3-dehydro-D-sphinganine + CO2
-
 ?
palmitoyl-CoA + L-serine
-
 Emiliania huxleyi CCMP374 CoA + 3-dehydro-D-sphinganine + CO2
-
 ?
pentadecanoyl-CoA + L-serine
-
 Emiliania huxleyi ?
-
 ?
pentadecanoyl-CoA + L-serine less than 50% activity compared to palmitoyl-CoA Emiliania huxleyi virus sp. ?
-
 ?
pentadecanoyl-CoA + L-serine less than 50% activity compared to palmitoyl-CoA Emiliania huxleyi virus sp. 201 ?
-
 ?
pentadecanoyl-CoA + L-serine
-
 Emiliania huxleyi CCMP374 ?
-
 ?

Subunits

Subunits Comment Organism
? x * 100000, SDS-PAGE Emiliania huxleyi

Synonyms

Synonyms Comment Organism
serine palmitoyltransferase
-
 Emiliania huxleyi
serine palmitoyltransferase
-
 Emiliania huxleyi virus sp.
SPT
-
 Emiliania huxleyi
SPT
-
 Emiliania huxleyi virus sp.

Cofactor

Cofactor Comment Organism Structure
pyridoxal 5'-phosphate
-
 Emiliania huxleyi
pyridoxal 5'-phosphate
-
 Emiliania huxleyi virus sp.

Expression

Organism Comment Expression
Emiliania huxleyi virus sp. the enzyme is highly expressed at early stages of infection of the host Emiliania huxleyi up