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Literature summary for 2.3.1.50 extracted from

  • Li, J.; Yin, J.; Rong, C.; Li, K.E.; Wu, J.X.; Huang, L.Q.; Zeng, H.Y.; Sahu, S.K.; Yao, N.
    Orosomucoid proteins interact with the small subunit of serine palmitoyltransferase and contribute to sphingolipid homeostasis and stress responses in Arabidopsis (2016), Plant Cell, 28, 3038-3051 .
    View publication on PubMedView publication on EuropePMC
Search for more literature for 2.3.1.50

Inhibitors

Inhibitors Comment Organism Structure
additional information orosomucoid proteins ORM1 and ORM2 inhibit the function of the small subunit ssSP and thus negatively regulate enzyme activity Arabidopsis thaliana

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
palmitoyl-CoA + L-serine Arabidopsis thaliana
-
 CoA + 3-dehydro-D-sphinganine + CO2
-
 ?

Organism

Organism UniProt Comment Textmining
Arabidopsis thaliana
-
 ecotype Col-0
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
palmitoyl-CoA + L-serine
-
 Arabidopsis thaliana CoA + 3-dehydro-D-sphinganine + CO2
-
 ?

Synonyms

Synonyms Comment Organism
LCB1 subunit Arabidopsis thaliana
LCB2a subunit Arabidopsis thaliana
LCB2b subunit Arabidopsis thaliana
serine palmitoyltransferase
-
 Arabidopsis thaliana
SPT
-
 Arabidopsis thaliana
ssSPT small subunit Arabidopsis thaliana

Cofactor

Cofactor Comment Organism Structure
pyridoxal 5'-phosphate
-
 Arabidopsis thaliana