Protein Variants | Comment | Organism |
---|---|---|
D115Y | non-synonymous single nucleotide variation, about 68% decrease in stability, about 82% decrease in activity | Macaca mulatta |
E155Q | non-synonymous single nucleotide variation, about 62% decrease in stability, about 22% decrease in activity | Macaca mulatta |
F175L | non-synonymous single nucleotide variation, about 50% decrease in stability, about 82% decrease in activity | Macaca mulatta |
G51A | non-synonymous single nucleotide variation, about 60% decrease in stability, about 45% decrease in activity | Macaca mulatta |
L89F | non-synonymous single nucleotide variation, about 56% decrease in stability, about 69% decrease in activity | Macaca mulatta |
L89F/D115Y | non-synonymous single nucleotide variation, about 95% decrease in stability, less about 95% decrease in activity | Macaca mulatta |
M82V | non-synonymous single nucleotide variation, about 68% decrease in stability, about 32% decrease in activity | Macaca mulatta |
additional information | identification of seven non-synonymous single nucleotide variations in NAT1 gene, showing compromised enzyme function, mainly through destabilization of NAT1 protein and consequent activity loss | Macaca mulatta |
R187Q | non-synonymous single nucleotide variation, about 27% decrease in stability, about 73% decrease in activity | Macaca mulatta |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Macaca mulatta | F6Q3X1 | - |
- |
Synonyms | Comment | Organism |
---|---|---|
NAT1 | - |
Macaca mulatta |