Inhibitors | Comment | Organism | Structure |
---|---|---|---|
peroxinitrite | rapid and irreversible inactivation | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
acetyl-CoA + an arylamine | Homo sapiens | important role in detoxification and metabolic activation of a variety of aromatic xenobiotics, including numerous carcinogens. Cellular generation of peroxinitrite may contribute to carcinogenesis and tumor progression by weakening key cellular defense enzymes such as NAT1 | CoA + a N-acetylarylamine | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
MCF-7 cell | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
acetyl-CoA + an arylamine | important role in detoxification and metabolic activation of a variety of aromatic xenobiotics, including numerous carcinogens. Cellular generation of peroxinitrite may contribute to carcinogenesis and tumor progression by weakening key cellular defense enzymes such as NAT1 | Homo sapiens | CoA + a N-acetylarylamine | - |
? |
Synonyms | Comment | Organism |
---|---|---|
NAT1 | - |
Homo sapiens |