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Literature summary for 2.3.1.48 extracted from

  • Deng, W.; Liu, C.; Pei, Y.; Deng, X.; Niu, L.; Cao, X.
    Involvement of the histone acetyltransferase AtHAC1 in the regulation of flowering time via repression of flowering locus C in Arabidopsis (2007), Plant Physiol., 143, 1660-1668.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

Cloned (Comment) Organism
gene hac1, genetic regulation analysis Arabidopsis thaliana

Protein Variants

Protein Variants Comment Organism
additional information construction of hac1 mutants by T-DNA insertion, lesions in AtHAC1 cause pleiotropic developmental defects, including delayed flowering, a shortened primary root, and partially reduced fertility, phenotypes, overview, mechanism, histone modifications of FLC chromatin are not affected by mutations in HAC1, HAC1 affects flowering time by epigenetic modification of factors upstream of the flowering locus C, overview Arabidopsis thaliana

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
histone + acetyl-CoA Arabidopsis thaliana histone acetylation is an important posttranslational modification correlated with gene activation, the HAC1 is involved in the regulation of flowering time via repression of flowering locus C, the enzyme participates in many physiological processes, including proliferation, differentiation, and apoptosis acetyl-histone + CoA
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?

Organism

Organism UniProt Comment Textmining
Arabidopsis thaliana
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-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
histone + acetyl-CoA
-
Arabidopsis thaliana acetyl-histone + CoA
-
?
histone + acetyl-CoA histone acetylation is an important posttranslational modification correlated with gene activation, the HAC1 is involved in the regulation of flowering time via repression of flowering locus C, the enzyme participates in many physiological processes, including proliferation, differentiation, and apoptosis Arabidopsis thaliana acetyl-histone + CoA
-
?

Synonyms

Synonyms Comment Organism
HAC1
-
Arabidopsis thaliana

Cofactor

Cofactor Comment Organism Structure
acetyl-CoA
-
Arabidopsis thaliana