Any feedback?
Literature summary for 2.3.1.48 extracted from
- Molecular basis for Gcn5/PCAF histone acetyltransferase selectivity for histone and nonhistone substrates (2003), Biochemistry, 42, 14366-14374.
Crystallization (Commentary)
| Crystallization (Comment) | Organism |
|---|---|
| crystal structure of tGcn5 bound to 19-residue histone H4 and P53 peptides | Tetrahymena sp. |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Tetrahymena sp. | - |
recombinant enzyme | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| acetyl-CoA + histone H3 | preferred substrate, the N-terminal substrate region plays an importsant role in enhanced affinity of the Gcn5/PCAF proteins for histone H3 | Tetrahymena sp. | peptide CoA + acetylhistone H3 peptide | - |
? |  |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| Gcn5/PCAF histone acetyltransferase | - |
Tetrahymena sp. |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
