Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
acetyl-CoA + histone | Tetrahymena thermophila | - |
CoA + acetylhistone | - |
r | |
acetyl-CoA + histone | Homo sapiens | involved in chromatin remodeling and DNA repair | CoA + acetylhistone | - |
r | |
acetyl-CoA + histone | Saccharomyces cerevisiae | involved in chromatin remodeling and DNA repair | CoA + acetylhistone | - |
r | |
acetyl-CoA + histone | Drosophila melanogaster | histone H3 is the preferred substrate | CoA + acetylhistone | - |
r | |
acetyl-CoA + histone | Mus musculus | histone H3 is the preferred substrate | CoA + acetylhistone | - |
r | |
acetyl-CoA + histone | Homo sapiens | histone H3 is the preferred substrate | CoA + acetylhistone | - |
r | |
acetyl-CoA + histone | Saccharomyces cerevisiae | histone H3 is the preferred substrate | CoA + acetylhistone | - |
r | |
acetyl-CoA + histone | Arabidopsis thaliana | histone H3 is the preferred substrate | CoA + acetylhistone | - |
r | |
acetyl-CoA + histone | Homo sapiens GCN5 | involved in chromatin remodeling and DNA repair | CoA + acetylhistone | - |
r | |
acetyl-CoA + histone | Homo sapiens GCN5 | histone H3 is the preferred substrate | CoA + acetylhistone | - |
r |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Arabidopsis thaliana | - |
gene Gcn5 | - |
Drosophila melanogaster | - |
gene Gcn5 | - |
Homo sapiens | - |
GCN5 | - |
Homo sapiens | - |
PCAF protein | - |
Homo sapiens GCN5 | - |
GCN5 | - |
Mus musculus | - |
gene Gcn5 | - |
Saccharomyces cerevisiae | - |
gene Gcn5 | - |
Tetrahymena thermophila | - |
protein p55 | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
acetyl-CoA + histone | - |
Drosophila melanogaster | CoA + acetylhistone | - |
r | |
acetyl-CoA + histone | - |
Mus musculus | CoA + acetylhistone | - |
r | |
acetyl-CoA + histone | - |
Homo sapiens | CoA + acetylhistone | - |
r | |
acetyl-CoA + histone | - |
Saccharomyces cerevisiae | CoA + acetylhistone | - |
r | |
acetyl-CoA + histone | - |
Arabidopsis thaliana | CoA + acetylhistone | - |
r | |
acetyl-CoA + histone | - |
Tetrahymena thermophila | CoA + acetylhistone | - |
r | |
acetyl-CoA + histone | involved in chromatin remodeling and DNA repair | Homo sapiens | CoA + acetylhistone | - |
r | |
acetyl-CoA + histone | involved in chromatin remodeling and DNA repair | Saccharomyces cerevisiae | CoA + acetylhistone | - |
r | |
acetyl-CoA + histone | histone H3 is the preferred substrate | Drosophila melanogaster | CoA + acetylhistone | - |
r | |
acetyl-CoA + histone | histone H3 is the preferred substrate | Mus musculus | CoA + acetylhistone | - |
r | |
acetyl-CoA + histone | histone H3 is the preferred substrate | Homo sapiens | CoA + acetylhistone | - |
r | |
acetyl-CoA + histone | histone H3 is the preferred substrate | Saccharomyces cerevisiae | CoA + acetylhistone | - |
r | |
acetyl-CoA + histone | histone H3 is the preferred substrate | Arabidopsis thaliana | CoA + acetylhistone | - |
r | |
acetyl-CoA + histone | - |
Homo sapiens GCN5 | CoA + acetylhistone | - |
r | |
acetyl-CoA + histone | involved in chromatin remodeling and DNA repair | Homo sapiens GCN5 | CoA + acetylhistone | - |
r | |
acetyl-CoA + histone | histone H3 is the preferred substrate | Homo sapiens GCN5 | CoA + acetylhistone | - |
r | |
acetyl-CoA + histone H3 | Gcn5 protein: preferred substrate, acetylation at Lys14 | Drosophila melanogaster | CoA + acetylhistone H3 | - |
r | |
acetyl-CoA + histone H3 | Gcn5 protein: preferred substrate, acetylation at Lys14 | Mus musculus | CoA + acetylhistone H3 | - |
r | |
acetyl-CoA + histone H3 | Gcn5 protein: preferred substrate, acetylation at Lys14 | Homo sapiens | CoA + acetylhistone H3 | - |
r | |
acetyl-CoA + histone H3 | Gcn5 protein: preferred substrate, acetylation at Lys14 | Saccharomyces cerevisiae | CoA + acetylhistone H3 | - |
r | |
acetyl-CoA + histone H3 | Gcn5 protein: preferred substrate, acetylation at Lys14 | Arabidopsis thaliana | CoA + acetylhistone H3 | - |
r | |
acetyl-CoA + histone H4 | - |
Tetrahymena thermophila | CoA + acetylhistone H4 | - |
r | |
acetyl-CoA + histone H4 | Gcn5 protein acetylates H4 when purified and presented separately to the enzyme at Lys8 and Lys16 | Drosophila melanogaster | CoA + acetylhistone H4 | - |
r | |
acetyl-CoA + histone H4 | Gcn5 protein acetylates H4 when purified and presented separately to the enzyme at Lys8 and Lys16 | Homo sapiens | CoA + acetylhistone H4 | - |
r | |
acetyl-CoA + histone H4 | Gcn5 protein acetylates H4 when purified and presented separately to the enzyme at Lys8 and Lys16 | Saccharomyces cerevisiae | CoA + acetylhistone H4 | - |
r | |
acetyl-CoA + histone H4 | Gcn5 protein acetylates H4 when purified and presented separately to the enzyme at Lys8 and Lys16 | Arabidopsis thaliana | CoA + acetylhistone H4 | - |
r | |
acetyl-CoA + protein p53 | - |
Homo sapiens | CoA + acetylprotein p53 | - |
r | |
additional information | Gcn5 is a coactivator of transcription | Drosophila melanogaster | ? | - |
? | |
additional information | Gcn5 is a coactivator of transcription | Mus musculus | ? | - |
? | |
additional information | Gcn5 is a coactivator of transcription | Homo sapiens | ? | - |
? | |
additional information | Gcn5 is a coactivator of transcription | Saccharomyces cerevisiae | ? | - |
? | |
additional information | Gcn5 is a coactivator of transcription | Arabidopsis thaliana | ? | - |
? | |
additional information | Gcn5 and PCAF protein are transcription cofactors | Drosophila melanogaster | ? | - |
? | |
additional information | Gcn5 and PCAF protein are transcription cofactors | Mus musculus | ? | - |
? | |
additional information | Gcn5 and PCAF protein are transcription cofactors | Homo sapiens | ? | - |
? | |
additional information | Gcn5 and PCAF protein are transcription cofactors | Saccharomyces cerevisiae | ? | - |
? | |
additional information | Gcn5 and PCAF protein are transcription cofactors | Arabidopsis thaliana | ? | - |
? | |
additional information | Gcn5 is a coactivator of transcription | Homo sapiens GCN5 | ? | - |
? | |
additional information | Gcn5 and PCAF protein are transcription cofactors | Homo sapiens GCN5 | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
factor acetyltransferase | enzyme form A is also able to acetylate nonhistone proteins, mostly transcription factors, overview | Drosophila melanogaster |
factor acetyltransferase | enzyme form A is also able to acetylate nonhistone proteins, mostly transcription factors, overview | Mus musculus |
factor acetyltransferase | enzyme form A is also able to acetylate nonhistone proteins, mostly transcription factors, overview | Homo sapiens |
factor acetyltransferase | enzyme form A is also able to acetylate nonhistone proteins, mostly transcription factors, overview | Saccharomyces cerevisiae |
factor acetyltransferase | enzyme form A is also able to acetylate nonhistone proteins, mostly transcription factors, overview | Arabidopsis thaliana |
factor acetyltransferase | enzyme form A is also able to acetylate nonhistone proteins, mostly transcription factors, overview | Tetrahymena thermophila |
FAT | when acetylating nonhistone transcription factor proteins, factor specific, overview | Drosophila melanogaster |
FAT | when acetylating nonhistone transcription factor proteins, factor specific, overview | Mus musculus |
FAT | when acetylating nonhistone transcription factor proteins, factor specific, overview | Homo sapiens |
FAT | when acetylating nonhistone transcription factor proteins, factor specific, overview | Saccharomyces cerevisiae |
FAT | when acetylating nonhistone transcription factor proteins, factor specific, overview | Arabidopsis thaliana |
FAT | when acetylating nonhistone transcription factor proteins, factor specific, overview | Tetrahymena thermophila |
HAT | - |
Drosophila melanogaster |
HAT | - |
Homo sapiens |
HAT | - |
Saccharomyces cerevisiae |
HAT | - |
Arabidopsis thaliana |
HAT | - |
Tetrahymena thermophila |
More | type A enzymes can be grouped into different families based on amino acid sequence comparison and binding motifs, overview | Drosophila melanogaster |
More | type A enzymes can be grouped into different families based on amino acid sequence comparison and binding motifs, overview | Homo sapiens |
More | type A enzymes can be grouped into different families based on amino acid sequence comparison and binding motifs, overview | Saccharomyces cerevisiae |
More | type A enzymes can be grouped into different families based on amino acid sequence comparison and binding motifs, overview | Arabidopsis thaliana |
More | type A enzymes can be grouped into different families based on amino acid sequence comparison and binding motifs, overview | Tetrahymena thermophila |
More | type A enzymes are localized in the nuclei and acetylate nucleosomal histones as well as nonhistone proteins, type B enzymes can be found in the cytoplasmic fraction and are responsible for acetylation of newly synthesized histones before their translocation into the nucleus for chromatin assembly during DNA replication | Drosophila melanogaster |
More | type A enzymes are localized in the nuclei and acetylate nucleosomal histones as well as nonhistone proteins, type B enzymes can be found in the cytoplasmic fraction and are responsible for acetylation of newly synthesized histones before their translocation into the nucleus for chromatin assembly during DNA replication | Homo sapiens |
More | type A enzymes are localized in the nuclei and acetylate nucleosomal histones as well as nonhistone proteins, type B enzymes can be found in the cytoplasmic fraction and are responsible for acetylation of newly synthesized histones before their translocation into the nucleus for chromatin assembly during DNA replication | Saccharomyces cerevisiae |
More | type A enzymes are localized in the nuclei and acetylate nucleosomal histones as well as nonhistone proteins, type B enzymes can be found in the cytoplasmic fraction and are responsible for acetylation of newly synthesized histones before their translocation into the nucleus for chromatin assembly during DNA replication | Arabidopsis thaliana |
More | type A enzymes are localized in the nuclei and acetylate nucleosomal histones as well as nonhistone proteins, type B enzymes can be found in the cytoplasmic fraction and are responsible for acetylation of newly synthesized histones before their translocation into the nucleus for chromatin assembly during DNA replication | Tetrahymena thermophila |