Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
additional information | high ionic strength required for maximal activity | Escherichia coli |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Escherichia coli | - |
- |
- |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
0.06 | - |
- |
Escherichia coli |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
acetyl-CoA + [acyl-carrier protein] | via acetyl-enzyme intermediate | Escherichia coli | CoA + acetyl-[acyl-carrier protein] | - |
r | |
acetyl-CoA + [acyl-carrier protein] | pantetheine, not 2-mercaptoethanol can replace [acyl-carrier-protein] | Escherichia coli | CoA + acetyl-[acyl-carrier protein] | - |
r | |
acetyl-CoA + [acyl-carrier protein] | acetyl-S-pantetheine can replace acetyl-CoA | Escherichia coli | CoA + acetyl-[acyl-carrier protein] | - |
r | |
butyryl-CoA + [acyl-carrier protein] | 9.8% activity of that with acetyl-CoA | Escherichia coli | CoA + butyryl-[acyl-carrier protein] | - |
? | |
hexanoyl-CoA + [acyl-carrier protein] | 4.6% activity of that with acetyl-CoA | Escherichia coli | CoA + hexanoyl-[acyl-carrier protein] | - |
? | |
additional information | no substrate: malonyl-CoA | Escherichia coli | ? | - |
? | |
additional information | in vertebrates, yeast and Mycobacteria acetyl transferase activity is a domain of the multifunctional polypeptide chains of fatty acid synthase EC 2.3.1.85 and EC 2.3.1.86 | Escherichia coli | ? | - |
? | |
propionyl-CoA + [acyl-carrier protein] | transacylation at 23.4% the rate of acetyl-CoA | Escherichia coli | CoA + propionyl-[acyl-carrier protein] | - |
? |
Subunits | Comment | Organism |
---|---|---|
More | vertebrates, yeast and Mycobacteria fatty acid synthetases contain all individual activities on one or two multifunctional polypeptide chains, plant, Escherichia coli and other prokaryotic fatty acid synthases are non-associated systems of individual enzymes | Escherichia coli |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
6.5 | - |
- |
Escherichia coli |