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Literature summary for 2.3.1.38 extracted from

  • Vagelos, R.P.
    Acyl group transfer (acyl carrier protein) (1973), The Enzymes, 3rd Ed. (Boyer, P. D. , ed. ), 8, 155-199.
No PubMed abstract available

Metals/Ions

Metals/Ions Comment Organism Structure
additional information high ionic strength required for maximal activity Escherichia coli

Organism

Organism UniProt Comment Textmining
Escherichia coli
-
-
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
0.06
-
-
Escherichia coli

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
acetyl-CoA + [acyl-carrier protein] via acetyl-enzyme intermediate Escherichia coli CoA + acetyl-[acyl-carrier protein]
-
r
acetyl-CoA + [acyl-carrier protein] pantetheine, not 2-mercaptoethanol can replace [acyl-carrier-protein] Escherichia coli CoA + acetyl-[acyl-carrier protein]
-
r
acetyl-CoA + [acyl-carrier protein] acetyl-S-pantetheine can replace acetyl-CoA Escherichia coli CoA + acetyl-[acyl-carrier protein]
-
r
butyryl-CoA + [acyl-carrier protein] 9.8% activity of that with acetyl-CoA Escherichia coli CoA + butyryl-[acyl-carrier protein]
-
?
hexanoyl-CoA + [acyl-carrier protein] 4.6% activity of that with acetyl-CoA Escherichia coli CoA + hexanoyl-[acyl-carrier protein]
-
?
additional information no substrate: malonyl-CoA Escherichia coli ?
-
?
additional information in vertebrates, yeast and Mycobacteria acetyl transferase activity is a domain of the multifunctional polypeptide chains of fatty acid synthase EC 2.3.1.85 and EC 2.3.1.86 Escherichia coli ?
-
?
propionyl-CoA + [acyl-carrier protein] transacylation at 23.4% the rate of acetyl-CoA Escherichia coli CoA + propionyl-[acyl-carrier protein]
-
?

Subunits

Subunits Comment Organism
More vertebrates, yeast and Mycobacteria fatty acid synthetases contain all individual activities on one or two multifunctional polypeptide chains, plant, Escherichia coli and other prokaryotic fatty acid synthases are non-associated systems of individual enzymes Escherichia coli

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
6.5
-
-
Escherichia coli