Activating Compound | Comment | Organism | Structure |
---|---|---|---|
carbamazepine | - |
Rattus norvegicus | |
estrogen | - |
Rattus norvegicus | |
ethanol | - |
Rattus norvegicus | |
ethinylestradiol | - |
Rattus norvegicus | |
norethandrolone | - |
Rattus norvegicus | |
Norethindrone | - |
Rattus norvegicus | |
Phenobarbitone | - |
Rattus norvegicus | |
Phenylbutazone | - |
Rattus norvegicus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
acetate | - |
Rattus norvegicus | |
adrenaline | - |
Rattus norvegicus | |
allopurinol | - |
Rattus norvegicus | |
aspirin | - |
Rattus norvegicus | |
Benserazide | - |
Rattus norvegicus | |
chlorpromazine | - |
Rattus norvegicus | |
estradiol | - |
Rattus norvegicus | |
estrogen | - |
Rattus norvegicus | |
fluoxetine | - |
Rattus norvegicus | |
heme | - |
Rattus norvegicus | |
lithium | - |
Rattus norvegicus | |
morphine | - |
Rattus norvegicus | |
naloxone | - |
Rattus norvegicus | |
noradrenaline | - |
Rattus norvegicus | |
paroxetine | - |
Rattus norvegicus | |
progesterone | - |
Rattus norvegicus | |
progestogen | - |
Rattus norvegicus | |
propranolol | - |
Rattus norvegicus | |
tryptophan | - |
Rattus norvegicus |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
mitochondrion | - |
Rattus norvegicus | 5739 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
succinyl-CoA + glycine | Rattus norvegicus | - |
5-aminolevulinate + CoA + CO2 | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Rattus norvegicus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Rattus norvegicus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
succinyl-CoA + glycine | - |
Rattus norvegicus | 5-aminolevulinate + CoA + CO2 | - |
? |
Synonyms | Comment | Organism |
---|---|---|
5-ALA synthase | - |
Rattus norvegicus |
5-ALAS | - |
Rattus norvegicus |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
pyridoxal 5'-phosphate | - |
Rattus norvegicus |
Organism | Comment | Expression |
---|---|---|
Rattus norvegicus | fasting (starvation) induces enzyme activity. Griseofulvin induces enzyme mRNA expression after 2 days of treatment | up |
General Information | Comment | Organism |
---|---|---|
metabolism | rate-limiting enzyme of heme biosynthesis | Rattus norvegicus |