Literature summary for 2.3.1.31 extracted from

Han, Y.K.; Lee, T.; Han, K.H.; Yun, S.H.; Lee, Y.W.
Functional analysis of the homoserine O-acetyltransferase gene and its identification as a selectable marker in Gibberella zeae (2004), Curr. Genet., 46, 205-212.

Search for more literature for 2.3.1.31

Application

Application	Comment	Organism
molecular biology	the HOA gene can be used as a selectable marker for transformation of Gibberella zeae	Fusarium graminearum

Cloned(Commentary)

Cloned (Comment)	Organism
subcloning in Escherichia coli	Fusarium graminearum

Protein Variants

Protein Variants	Comment	Organism
additional information	construction of the methionine auxotroph mutant strain Z43R3912 by restriction enzyme-mediated integration REMI, the mutant strain shows pleiotrophic phenotypes including reduced virulence on host cereal plants and lack of sexual development, overview, mutation is tagged with the hygromycin B resistance marker and insertion can be located in the HOA gene ancoding the enzyme, complementation of the mutants methionine auxotrophy by expression of metE and GrzmetE genes from Aspergillus nidulans	Fusarium graminearum

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
acetyl-CoA + L-homoserine	Fusarium graminearum	a key enzyme in methionine biosynthesis	CoA + O-acetyl-L-homoserine	-	?

Organism

Organism	UniProt	Comment	Textmining
Fusarium graminearum	-	anamorph: Fusarium graminearum, wild-type strain Z03643	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
acetyl-CoA + L-homoserine	-	Fusarium graminearum	CoA + O-acetyl-L-homoserine	-	?
acetyl-CoA + L-homoserine	a key enzyme in methionine biosynthesis	Fusarium graminearum	CoA + O-acetyl-L-homoserine	-	?

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)