Organism | UniProt | Comment | Textmining |
---|---|---|---|
Xanthomonas campestris pv. campestris | Q4URQ0 | cf. EC 2.3.1.180 | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
11350 | - |
substrate isobutanoyl-CoA, pH 7, temperature not specified in the publication | Xanthomonas campestris pv. campestris |
17350 | - |
substrate isovaleryl-CoA, pH 7, temperature not specified in the publication | Xanthomonas campestris pv. campestris |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
isobutanoyl-CoA + malonyl-[acyl-carrier protein] | - |
Xanthomonas campestris pv. campestris | 5-methyl-3-oxohexanoyl-[acyl-carrier-protein] + CoA + CO2 | - |
? | |
isovaleryl-CoA + malonyl-[acyl-carrier protein] | - |
Xanthomonas campestris pv. campestris | ? + CoA + CO2 | - |
? | |
additional information | FabH in addition uses acetyl-CoA, butanoyl-CoA, hexanoyl-CoA, octanoyl-CoA, or decanoyl-CoA as a primer as a primer to initiate fatty acid synthesis, reaction of EC 2.3.1.180, and also condenses short-chain acyl-ACPs with malonyl-ACP to produce longer acyl-ACPs | Xanthomonas campestris pv. campestris | ? | - |
- |
General Information | Comment | Organism |
---|---|---|
physiological function | FabH is able to condense branched-chain acyl-CoAs with malonyl-ACP to initiate branched-chain fatty acid synthesis. The fabH gene is essential for growth of Xanthomonas campestris. It can be replaced with Escherichia coli fabH, and transgenic strains mutants fail to produce branched-chain fatty acids. Xanthomonas campestris FabH mutants lost the ability to produce cis-11-methyl-2-dodecenoic acid | Xanthomonas campestris pv. campestris |