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Literature summary for 2.3.1.297 extracted from
- Enzymatic synthesis of ceramide (1966), Biochim. Biophys. Acta, 125, 542-547 .
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| Ca2+ | - |
Cavia porcellus |  |
| Ca2+ | - |
Gallus gallus | |
| Mn2+ | - |
Cavia porcellus | |
| Mn2+ | - |
Gallus gallus | |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| microsome | - |
Gallus gallus | - |
- |
| microsome | - |
Cavia porcellus | - |
- |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Mg2+ | no absolute requirement for metal ions, magnesium ions stimulate the reaction | Gallus gallus | |
| Mg2+ | no absolute requirement for metal ions, magnesium ions stimulate the reaction | Cavia porcellus | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Cavia porcellus | - |
- |
- |
| Gallus gallus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| brain | - |
Cavia porcellus | - |
| liver | - |
Gallus gallus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| DL-erythro-sphingosine + nervonoyl-CoA | both the threo and erythro isomers are active as acceptors, the latter is preferred | Gallus gallus | N-nervonoylsphingosine + CoA | - |
? | |
| DL-erythro-sphingosine + nervonoyl-CoA | both the threo and erythro isomers are active as acceptors, the latter is preferred | Cavia porcellus | N-nervonoylsphingosine + CoA | - |
? | |
| DL-threo-sphingosine + nervonoyl-CoA | both the threo and erythro isomers are active as acceptors, the latter is preferred | Gallus gallus | N-nervonoylsphingosine + CoA | - |
? | |
| DL-threo-sphingosine + nervonoyl-CoA | both the threo and erythro isomers are active as acceptors, the latter is preferred | Cavia porcellus | N-nervonoylsphingosine + CoA | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| acyl-CoA : sphingosine N-acyltramferase | - |
Gallus gallus |
| acyl-CoA : sphingosine N-acyltramferase | - |
Cavia porcellus |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 7.5 | - |
- |
Gallus gallus |
| 7.5 | - |
- |
Cavia porcellus |
pH Range
| pH Minimum | pH Maximum | Comment | Organism |
|---|---|---|---|
| 6.5 | 8.2 | about 50% of maximal activity within this range | Gallus gallus |
| 6.5 | 8.2 | about 50% of maximal activity within this range | Cavia porcellus |
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Release 2023.1 (January 2023)
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