Cloned (Comment) | Organism |
---|---|
expressed in Mycobacterium bovis BCG vaccine strain 1173P2 | Mycobacterium tuberculosis |
Protein Variants | Comment | Organism |
---|---|---|
G269S | the S mutation may affect targeting of the inhibitor thiolactomycin to the enzyme | Mycobacterium tuberculosis |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
thiolactomycin | - |
Mycobacterium tuberculosis |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytosol | - |
Mycobacterium tuberculosis | 5829 | - |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Mycobacterium tuberculosis | the enzyme catalyzes the condensation steps from C18 to C34 long-chain fatty acids | ? | - |
? | |
additional information | Mycobacterium tuberculosis H37Rv | the enzyme catalyzes the condensation steps from C18 to C34 long-chain fatty acids | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mycobacterium tuberculosis | - |
- |
- |
Mycobacterium tuberculosis H37Rv | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | the enzyme catalyzes the condensation steps from C18 to C34 long-chain fatty acids | Mycobacterium tuberculosis | ? | - |
? | |
additional information | the enzyme catalyzes the condensation steps from C18 to C34 long-chain fatty acids | Mycobacterium tuberculosis H37Rv | ? | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | x * 43000, SDS-PAGE | Mycobacterium tuberculosis |
Synonyms | Comment | Organism |
---|---|---|
beta-ketoacyl-acyl-carrier protein synthase | - |
Mycobacterium tuberculosis |
KasA | - |
Mycobacterium tuberculosis |
Rv2245 | - |
Mycobacterium tuberculosis |
General Information | Comment | Organism |
---|---|---|
metabolism | the enzyme is involved in fatty acid and mycolic acid biosynthesis | Mycobacterium tuberculosis |