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Literature summary for 2.3.1.293 extracted from

  • Bhatt, A.; Kremer, L.; Dai, A.Z.; Sacchettini, J.C.; Jacobs, W.R.
    Conditional depletion of KasA, a key enzyme of mycolic acid biosynthesis, leads to mycobacterial cell lysis (2005), J. Bacteriol., 187, 7596-7606 .
    View publication on PubMedView publication on EuropePMC
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Organism

Organism UniProt Comment Textmining
Mycolicibacterium smegmatis
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Mycolicibacterium smegmatis mc2155
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Synonyms

Synonyms Comment Organism
beta-ketoacyl-acyl carrier protein synthase
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 Mycolicibacterium smegmatis
KasA
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 Mycolicibacterium smegmatis

General Information

General Information Comment Organism
malfunction depletion of the enzyme leads to mycobacterial cell lysis and inhibition of alpha and epoxy mycolate biosynthesis and to accumulation of alpha'-mycolates Mycolicibacterium smegmatis
metabolism key enzyme of mycolic acid biosynthesis Mycolicibacterium smegmatis