Application | Comment | Organism |
---|---|---|
medicine | long-chain ceramides are upregulated whereas very long-chain ceramides are downregulated in cell lines, mouse animal model, and patients with cystic fibrosis, compared with their controls. Treatment with fenretinide decreases the levels of long-chain ceramides and increases the levels of very long-chain ceramides | Mus musculus |
medicine | long-chain ceramides are upregulated whereas very long-chain ceramides are downregulated in cell lines, mouse animal model, and patients with cystic fibrosis, compared with their controls. Treatment with fenretinide decreases the levels of long-chain ceramides and increases the levels of very long-chain ceramides | Homo sapiens |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | Q8N5B7 | - |
- |
Mus musculus | Q9D6K9 | - |
- |
Organism | Comment | Expression |
---|---|---|
Mus musculus | presence of fenritinide leads to transcriptional downregulation of Cers5 | down |
Homo sapiens | presence of fenritinide leads to transcriptional downregulation of Cers5 | down |