Organism | UniProt | Comment | Textmining |
---|---|---|---|
Schizosaccharomyces pombe | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
[histone H3]-N6-acetyl-L-lysine9 + NAD+ + H2O | overall reaction | Schizosaccharomyces pombe | [histone H3]-L-lysine9 + 2''-O-acetyl-ADP-D-ribose + nicotinamide | - |
? |
Synonyms | Comment | Organism |
---|---|---|
Clr3 | - |
Schizosaccharomyces pombe |
HDAC | - |
Schizosaccharomyces pombe |
histone deacetylase | - |
Schizosaccharomyces pombe |
Sir2 | - |
Schizosaccharomyces pombe |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NAD+ | - |
Schizosaccharomyces pombe |
General Information | Comment | Organism |
---|---|---|
physiological function | maintenance of [histone H3]-L-lysine9 methylation at centromeres requires the histone deacetylases Sir2 and Clr3 | Schizosaccharomyces pombe |