Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
[protein]-N6-acetyl-L-lysine + NAD+ + H2O | Drosophila melanogaster | overall reaction | [protein]-L-lysine + 2''-O-acetyl-ADP-D-ribose + nicotinamide | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Drosophila melanogaster | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
[protein]-N6-acetyl-L-lysine + NAD+ + H2O | overall reaction | Drosophila melanogaster | [protein]-L-lysine + 2''-O-acetyl-ADP-D-ribose + nicotinamide | - |
? |
Synonyms | Comment | Organism |
---|---|---|
silent information regulator 2 | - |
Drosophila melanogaster |
Sir2 | - |
Drosophila melanogaster |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NAD+ | dependent on | Drosophila melanogaster |
General Information | Comment | Organism |
---|---|---|
physiological function | increased enzyme expression of extends life span in a dose-dependent manner | Drosophila melanogaster |