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Literature summary for 2.3.1.286 extracted from

  • Onyango, P.; Celic, I.; McCaffery, J.M.; Boeke, J.D.; Feinberg, A.P.
    SIRT3, a human SIR2 homologue, is an NAD-dependent deacetylase localized to mitochondria (2002), Proc. Natl. Acad. Sci. USA, 99, 13653-13658.
    View publication on PubMedView publication on EuropePMC
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Cloned(Commentary)

Cloned (Comment) Organism
-
 Homo sapiens

Localization

Localization Comment Organism GeneOntology No. Textmining
mitochondrion SIRT3 is localized to the inner membrane of the mitochondria Homo sapiens 5739
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
NAD+ + [chicken erythrocyte histone]-N6-acetyl-L-lysine Homo sapiens
-
 nicotinamide + [protein]-L-lysine + 2'-O-acetyl-ADP ribose
-
 ?

Organism

Organism UniProt Comment Textmining
Homo sapiens Q9NTG7
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
NAD+ + [chicken erythrocyte histone]-N6-acetyl-L-lysine
-
 Homo sapiens nicotinamide + [protein]-L-lysine + 2'-O-acetyl-ADP ribose
-
 ?

Synonyms

Synonyms Comment Organism
SIRT3
-
 Homo sapiens