BRENDA - Reference to 2.3.1.286; Id = 730024

NAD+ + [protein]-N6-succinyl-L-lysine

Homo sapiens

-

nicotinamide + [protein]-L-lysine + 2'-O-succinyl-ADP-ribose

-

?

Homo sapiens

Q8IXJ6

-

Homo sapiens

Q96EB6

-

Homo sapiens

Q9NTG7

-

N6-acetyl-L-lysine + NAD+ + H2O = [protein]-L-lysine + 2''-O-acetyl-ADP-D-ribose + nicotinamide

broad specificity with respect to chain length of the acyl chain

Homo sapiens

additional information

no activity with the crotonylated histone H3 peptide QTAR(N6-crotonyl)KSTGG

730024

Homo sapiens

?

-

additional information

no activity with the succinylated histone H3 peptide QTAR(N6-succinyl)KSTGG

730024

Homo sapiens

?

-

NAD+ + QTAR(N6-acetyl)KSTGG

acetylated histone H3 peptide

730024

Homo sapiens

nicotinamide + QTARKSTGG + 2'-O-acetyl-ADP-ribose

-

?

NAD+ + QTAR(N6-butyryl)KSTGG

butyrylated histone H3 peptide

730024

Homo sapiens

nicotinamide + QTARKSTGG + 2'-O-butyryl-ADP-ribose

-

?

NAD+ + QTAR(N6-butyryl)KSTGG

butyrylated histone H3 peptide, about 20% compared to the activity with the acetylated peptide

730024

Homo sapiens

nicotinamide + QTARKSTGG + 2'-O-butyryl-ADP-ribose

-

?

NAD+ + QTAR(N6-butyryl)KSTGG

butyrylated histone H3 peptide, about 5% compared to the activity with the acetylated peptide

730024

Homo sapiens

nicotinamide + QTARKSTGG + 2'-O-butyryl-ADP-ribose

-

?

NAD+ + QTAR(N6-crotonyl)KSTGG

crotonylated histone H3 peptide, about 20% compared to the activity with the acetylated peptide

730024

Homo sapiens

nicotinamide + QTARKSTGG + 2'-O-crotonyl-ADP-ribose

-

?

NAD+ + QTAR(N6-crotonyl)KSTGG

crotonylated histone H3 peptide, about 30% compared to the activity with the acetylated or hexanoylated peptide

730024

Homo sapiens

nicotinamide + QTARKSTGG + 2'-O-crotonyl-ADP-ribose

-

?

NAD+ + QTAR(N6-decanoyl)KSTGG

decanoylated histone H3 peptide, about 50% compared to the activity with the acetylated peptide

730024

Homo sapiens

nicotinamide + QTARKSTGG + 2'-O-decanoyl-ADP-ribose

-

?

NAD+ + QTAR(N6-decanoyl)KSTGG

decanoylated histone H3 peptide, about 65% compared to the activity with the acetylated peptide

730024

Homo sapiens

nicotinamide + QTARKSTGG + 2'-O-decanoyl-ADP-ribose

-

?

NAD+ + QTAR(N6-decanoyl)KSTGG

decanoylated histone H3 peptide, about 80% compared to the activity with the acetylated or hexanoylated peptide

730024

Homo sapiens

nicotinamide + QTARKSTGG + 2'-O-decanoyl-ADP-ribose

-

?

NAD+ + QTAR(N6-decanoyl)KSTGG

myristoylated histone H3 peptide, about 50% compared to the activity with the acetylated or hexanoylated peptide

730024

Homo sapiens

nicotinamide + QTARKSTGG + 2'-O-decanoyl-ADP-ribose

-

?

NAD+ + QTAR(N6-decanoyl)KSTGG

myristoylated histone H3 peptide, about 65% compared to the activity with the acetylated or hexanoylated peptide

730024

Homo sapiens

nicotinamide + QTARKSTGG + 2'-O-decanoyl-ADP-ribose

-

?

NAD+ + QTAR(N6-dodecanoyl)KSTGG

dodecanoylated histone H3 peptide, about 30% compared to the activity with the acetylated peptide

730024

Homo sapiens

nicotinamide + QTARKSTGG + 2'-O-dodecanoyl-ADP-ribose

-

?

NAD+ + QTAR(N6-dodecanoyl)KSTGG

dodecanoylated histone H3 peptide, about 60% compared to the activity with the acetylated or hexanoylated peptide

730024

Homo sapiens

nicotinamide + QTARKSTGG + 2'-O-dodecanoyl-ADP-ribose

-

?

NAD+ + QTAR(N6-dodecanoyl)KSTGG

dodecanoylated histone H3 peptide, about 65% compared to the activity with the acetylated peptide

730024

Homo sapiens

nicotinamide + QTARKSTGG + 2'-O-dodecanoyl-ADP-ribose

-

?

NAD+ + QTAR(N6-hexanoyl)KSTGG

hexanoylated histone H3 peptide

730024

Homo sapiens

nicotinamide + QTARKSTGG + 2'-O-hexanoyl-ADP-ribose

-

?

NAD+ + QTAR(N6-hexanoyl)KSTGG

hexanoylated histone H3 peptide, about 20% compared to the activity with the acetylated peptide

730024

Homo sapiens

nicotinamide + QTARKSTGG + 2'-O-propionyl-ADP-ribose

-

?

NAD+ + QTAR(N6-hexanoyl)KSTGG

hexanoylated histone H3 peptide, about 40% compared to the activity with the acetylated peptide

730024

Homo sapiens

nicotinamide + QTARKSTGG + 2'-O-propionyl-ADP-ribose

-

?

NAD+ + QTAR(N6-myristoyl)KSTGG

myristoylated histone H3 peptide, about 45% compared to the activity with the acetylated or hexanoylated peptide

730024

Homo sapiens

nicotinamide + QTARKSTGG + 2'-O-myristoyl-ADP-ribose

-

?

NAD+ + QTAR(N6-octanoyl)KSTGG

octanoylated histone H3 peptide

730024

Homo sapiens

nicotinamide + QTARKSTGG + 2'-O-octanoyl-ADP-ribose

-

?

NAD+ + QTAR(N6-octanoyl)KSTGG

octanoylated histone H3 peptide, about 35% compared to the activity with the acetylated peptide

730024

Homo sapiens

nicotinamide + QTARKSTGG + 2'-O-octanoyl-ADP-ribose

-

?

NAD+ + QTAR(N6-octanoyl)KSTGG

octanoylated histone H3 peptide, about 55% compared to the activity with the acetylated peptide

730024

Homo sapiens

nicotinamide + QTARKSTGG + 2'-O-octanoyl-ADP-ribose

-

?

NAD+ + QTAR(N6-palmitoyl)KSTGG

myristoylated histone H3 peptide, about 30% compared to the activity with the acetylated or hexanoylated peptide

730024

Homo sapiens

nicotinamide + QTARKSTGG + 2'-O-palmitoyl-ADP-ribose

-

?

NAD+ + QTAR(N6-propionyl)KSTGG

propionylated histone H3 peptide, about 10% compared to the activity with the acetylated peptide

730024

Homo sapiens

nicotinamide + QTARKSTGG + 2'-O-propionyl-ADP-ribose

-

?

NAD+ + QTAR(N6-propionyl)KSTGG

propionylated histone H3 peptide, about 40% compared to the activity with the acetylated peptide

730024

Homo sapiens

nicotinamide + QTARKSTGG + 2'-O-propionyl-ADP-ribose

-

?

NAD+ + QTAR(N6-propionyl)KSTGG

propionylated histone H3 peptide, about 60% compared to the activity with the acetylated or hexanoylated peptide

730024

Homo sapiens

nicotinamide + QTARKSTGG + 2'-O-propionyl-ADP-ribose

-

?

NAD+ + QTAR(N6-succinyl)KSTGG

succinylated histone H3 peptide, about 10% compared to the activity with the acetylated peptide

730024

Homo sapiens

nicotinamide + QTARKSTGG + 2'-O-succinyl-ADP-ribose

-

?

NAD+ + [protein]-N6-succinyl-L-lysine

-

730024

Homo sapiens

nicotinamide + [protein]-L-lysine + 2'-O-succinyl-ADP-ribose

-

?

NAD+ + [protein]-N6-succinyl-L-lysine

Homo sapiens

-

nicotinamide + [protein]-L-lysine + 2'-O-succinyl-ADP-ribose

-

?

additional information

no activity with the crotonylated histone H3 peptide QTAR(N6-crotonyl)KSTGG

730024

Homo sapiens

?

-

additional information

no activity with the succinylated histone H3 peptide QTAR(N6-succinyl)KSTGG

730024

Homo sapiens

?

-

NAD+ + QTAR(N6-acetyl)KSTGG

acetylated histone H3 peptide

730024

Homo sapiens

nicotinamide + QTARKSTGG + 2'-O-acetyl-ADP-ribose

-

?

NAD+ + QTAR(N6-butyryl)KSTGG

butyrylated histone H3 peptide

730024

Homo sapiens

nicotinamide + QTARKSTGG + 2'-O-butyryl-ADP-ribose

-

?

NAD+ + QTAR(N6-butyryl)KSTGG

butyrylated histone H3 peptide, about 20% compared to the activity with the acetylated peptide

730024

Homo sapiens

nicotinamide + QTARKSTGG + 2'-O-butyryl-ADP-ribose

-

?

NAD+ + QTAR(N6-butyryl)KSTGG

butyrylated histone H3 peptide, about 5% compared to the activity with the acetylated peptide

730024

Homo sapiens

nicotinamide + QTARKSTGG + 2'-O-butyryl-ADP-ribose

-

?

NAD+ + QTAR(N6-crotonyl)KSTGG

crotonylated histone H3 peptide, about 20% compared to the activity with the acetylated peptide

730024

Homo sapiens

nicotinamide + QTARKSTGG + 2'-O-crotonyl-ADP-ribose

-

?

NAD+ + QTAR(N6-crotonyl)KSTGG

crotonylated histone H3 peptide, about 30% compared to the activity with the acetylated or hexanoylated peptide

730024

Homo sapiens

nicotinamide + QTARKSTGG + 2'-O-crotonyl-ADP-ribose

-

?

NAD+ + QTAR(N6-decanoyl)KSTGG

decanoylated histone H3 peptide, about 50% compared to the activity with the acetylated peptide

730024

Homo sapiens

nicotinamide + QTARKSTGG + 2'-O-decanoyl-ADP-ribose

-

?

NAD+ + QTAR(N6-decanoyl)KSTGG

decanoylated histone H3 peptide, about 65% compared to the activity with the acetylated peptide

730024

Homo sapiens

nicotinamide + QTARKSTGG + 2'-O-decanoyl-ADP-ribose

-

?

NAD+ + QTAR(N6-decanoyl)KSTGG

decanoylated histone H3 peptide, about 80% compared to the activity with the acetylated or hexanoylated peptide

730024

Homo sapiens

nicotinamide + QTARKSTGG + 2'-O-decanoyl-ADP-ribose

-

?

NAD+ + QTAR(N6-decanoyl)KSTGG

myristoylated histone H3 peptide, about 50% compared to the activity with the acetylated or hexanoylated peptide

730024

Homo sapiens

nicotinamide + QTARKSTGG + 2'-O-decanoyl-ADP-ribose

-

?

NAD+ + QTAR(N6-decanoyl)KSTGG

myristoylated histone H3 peptide, about 65% compared to the activity with the acetylated or hexanoylated peptide

730024

Homo sapiens

nicotinamide + QTARKSTGG + 2'-O-decanoyl-ADP-ribose

-

?

NAD+ + QTAR(N6-dodecanoyl)KSTGG

dodecanoylated histone H3 peptide, about 30% compared to the activity with the acetylated peptide

730024

Homo sapiens

nicotinamide + QTARKSTGG + 2'-O-dodecanoyl-ADP-ribose

-

?

NAD+ + QTAR(N6-dodecanoyl)KSTGG

dodecanoylated histone H3 peptide, about 60% compared to the activity with the acetylated or hexanoylated peptide

730024

Homo sapiens

nicotinamide + QTARKSTGG + 2'-O-dodecanoyl-ADP-ribose

-

?

NAD+ + QTAR(N6-dodecanoyl)KSTGG

dodecanoylated histone H3 peptide, about 65% compared to the activity with the acetylated peptide

730024

Homo sapiens

nicotinamide + QTARKSTGG + 2'-O-dodecanoyl-ADP-ribose

-

?

NAD+ + QTAR(N6-hexanoyl)KSTGG

hexanoylated histone H3 peptide

730024

Homo sapiens

nicotinamide + QTARKSTGG + 2'-O-hexanoyl-ADP-ribose

-

?

NAD+ + QTAR(N6-hexanoyl)KSTGG

hexanoylated histone H3 peptide, about 20% compared to the activity with the acetylated peptide

730024

Homo sapiens

nicotinamide + QTARKSTGG + 2'-O-propionyl-ADP-ribose

-

?

NAD+ + QTAR(N6-hexanoyl)KSTGG

hexanoylated histone H3 peptide, about 40% compared to the activity with the acetylated peptide

730024

Homo sapiens

nicotinamide + QTARKSTGG + 2'-O-propionyl-ADP-ribose

-

?

NAD+ + QTAR(N6-myristoyl)KSTGG

myristoylated histone H3 peptide, about 45% compared to the activity with the acetylated or hexanoylated peptide

730024

Homo sapiens

nicotinamide + QTARKSTGG + 2'-O-myristoyl-ADP-ribose

-

?

NAD+ + QTAR(N6-octanoyl)KSTGG

octanoylated histone H3 peptide

730024

Homo sapiens

nicotinamide + QTARKSTGG + 2'-O-octanoyl-ADP-ribose

-

?

NAD+ + QTAR(N6-octanoyl)KSTGG

octanoylated histone H3 peptide, about 35% compared to the activity with the acetylated peptide

730024

Homo sapiens

nicotinamide + QTARKSTGG + 2'-O-octanoyl-ADP-ribose

-

?

NAD+ + QTAR(N6-octanoyl)KSTGG

octanoylated histone H3 peptide, about 55% compared to the activity with the acetylated peptide

730024

Homo sapiens

nicotinamide + QTARKSTGG + 2'-O-octanoyl-ADP-ribose

-

?

NAD+ + QTAR(N6-palmitoyl)KSTGG

myristoylated histone H3 peptide, about 30% compared to the activity with the acetylated or hexanoylated peptide

730024

Homo sapiens

nicotinamide + QTARKSTGG + 2'-O-palmitoyl-ADP-ribose

-

?

NAD+ + QTAR(N6-propionyl)KSTGG

propionylated histone H3 peptide, about 10% compared to the activity with the acetylated peptide

730024

Homo sapiens

nicotinamide + QTARKSTGG + 2'-O-propionyl-ADP-ribose

-

?

NAD+ + QTAR(N6-propionyl)KSTGG

propionylated histone H3 peptide, about 40% compared to the activity with the acetylated peptide

730024

Homo sapiens

nicotinamide + QTARKSTGG + 2'-O-propionyl-ADP-ribose

-

?

NAD+ + QTAR(N6-propionyl)KSTGG

propionylated histone H3 peptide, about 60% compared to the activity with the acetylated or hexanoylated peptide

730024

Homo sapiens

nicotinamide + QTARKSTGG + 2'-O-propionyl-ADP-ribose

-

?

NAD+ + QTAR(N6-succinyl)KSTGG

succinylated histone H3 peptide, about 10% compared to the activity with the acetylated peptide

730024

Homo sapiens

nicotinamide + QTARKSTGG + 2'-O-succinyl-ADP-ribose

-

?

NAD+ + [protein]-N6-succinyl-L-lysine

-

730024

Homo sapiens

nicotinamide + [protein]-L-lysine + 2'-O-succinyl-ADP-ribose

-

?

752056

Swygert

SIR proteins create compact h ...

Saccharomyces cerevisiae

Proc. Natl. Acad. Sci. USA

115

12447-12452

2018

-

1

-

1

-

1

-

1

-

1

-

1

-

749818

Anand

A Sir2 family protein Rv1151c ...

Mycobacterium tuberculosis

Biochem. Biophys. Res. Commun.

493

1204-1209

2017

-

1

-

1

-

5

-

1

-

1

-

1

-

1

-

1

-

1

-

1

-

751295

Kang

HST1 increases replicative li ...

Saccharomyces cerevisiae, Saccharomyces cerevisiae BY4741

J. Microbiol.

55

123-129

2017

-

2

-

59

-

4

-

1

-

1

-

2

-

4

-

1

-

737969

Bhalla

Functional characterization of ...

Homo sapiens

Cancer Biol. Ther.

17

300-309

2016

-

2

-

1

-

2

-

4

-

1

-

1

-

1

-

2

-

1

-

4

-

1

-

1

-

738942

Song

Deacetylation assays to unrave ...

Homo sapiens

J. Vis. Exp.

108

53563

2016

-

1

-

1

-

1

-

1

-

1

-

1

-

1

-

739439

Tulino

SIRT1 activity is linked to it ...

Mus musculus

PLoS ONE

11

e0145425

2016

1

-

3

-

1

-

4

-

1

-

1

-

1

-

1

-

1

-

4

-

1

-

1

-

1

-

739686

Aragones

Dietary proanthocyanidins boos ...

Rattus norvegicus

Sci. Rep.

6

24977

2016

-

1

-

2

-

2

-

2

-

1

-

2

-

2

-

1

-

729603

Di Fruscia

The discovery of a highly sele ...

Homo sapiens

ChemMedChem

10

69-82

2015

-

1

-

7

-

1

-

1

-

1

-

1

-

1

-

7

-

1

-

7

1

-

1

-

1

-

1

-

737389

Rumpf

Seeding for sirtuins: microsee ...

Homo sapiens

Acta Crystallogr. Sect. F

71

1498-1510

2015

-

1

-

1

-

2

-

3

-

1

-

2

-

1

-

2

-

2

-

2

-

2

-

2

-

738108

Yang

SIRT3-dependent GOT2 acetylati ...

Homo sapiens

EMBO J.

34

1110-1125

2015

-

1

-

1

-

2

-

1

-

1

-

1

-

1

-

1

-

1

-

1

-

1

-

738438

Lee

Sirtuin 1 (SIRT1) deacetylase ...

Homo sapiens

J. Agric. Food Chem.

63

7361-7370

2015

-

1

-

2

-

4

-

1

-

1

-

4

-

1

-

1

-

738661

Lu

Prolonged fasting identifies h ...

Mus musculus

J. Biol. Chem.

290

2466-2476

2015

-

1

-

1

-

1

-

1

-

1

-

1

-

1

-

1

-

1

-

2

-

738674

Weiser

Propofol inhibits SIRT2 deacet ...

Homo sapiens, Rattus norvegicus

J. Biol. Chem.

290

8559-8568

2015

-

13

-

2

-

4

-

1

-

2

-

13

-

2

-

1

-

2

-

739214

Fang

Enhancement of NAD+-dependent ...

Homo sapiens, Rattus norvegicus

Oncotarget

6

42879-42891

2015

-

6

-

2

-

4

-

3

-

2

-

2

-

2

-

6

-

2

-

3

-

2

-

739412

Zhang

SIRT3 and SIRT5 regulate the e ...

Mus musculus

PLoS ONE

10

e0122297

2015

-

1

-

1

-

3

-

1

-

1

-

1

-

1

-

1

-

1

-

739668

Teng

Efficient demyristoylase activ ...

Homo sapiens

Sci. Rep.

5

8529

2015

-

1

-

2

-

2

-

1

-

1

-

9

-

2

-

1

-

1

-

2

-

2

-

1

-

9

-

2

-

2

739727

Pasha

-

Amberlyst-15 catalyzed Povarov ...

Homo sapiens

Tetrahedron Lett.

56

2289-2292

2015

-

6

-

1

-

6

-

739745

Cattelan

NAD+-dependent SIRT1 deactivat ...

Rattus norvegicus

Vascul. Pharmacol.

70

35-44

2015

1

-

1

-

1

-

2

-

2

-

1

-

1

-

1

-

1

-

1

-

1

-

2

-

1

-

1

-

729498

Wang

Down-regulation of sirtuin 3 i ...

Homo sapiens

BMC Cancer

0

0000

2014

-

1

-

1

-

1

-

1

-

1

-

729674

Khanfar

Development and characterizati ...

Homo sapiens

Eur. J. Med. Chem.

76

414-426

2014

-

1

-

24

-

2

-

1

-

24

-

1

-

24

-

1

-

729680

Kokkonen

Quantitative insights for the ...

Homo sapiens

Eur. J. Pharm. Sci.

59

12-19

2014

-

1

-

13

-

2

-

1

-

1

-

13

-

1

-

730474

Lutz

Distinct patterns of sirtuin e ...

Homo sapiens

Neuromolecular Med.

16

405-414

2014

-

1

-

1

-

1

-

730679

Guan

Mechanism of inhibition of the ...

Homo sapiens

PLoS One

15

e107729

2014

-

2

-

3

-

2

-

4

-

4

-

2

-

730980

Yamagata

Structural basis for potent in ...

Homo sapiens

Structure

22

345-352

2014

-

1

-

1

-

2

-

1

-

1

-

1

-

1

-

729164

Madabushi

Histone deacetylase SIRT1 modu ...

Homo sapiens

Biochem. J.

456

89-98

2013

-

1

-

1

-

3

-

1

-

2

-

1

-

1

-

1

-

2

-

730024

Feldman

Activation of the protein deac ...

Homo sapiens

J. Biol. Chem.

288

31350-31356

2013

-

3

-

3

-

1

-

34

-

3

-

34

-

730166

Zhao

The 2.5 A crystal structure of ...

Homo sapiens

J. Med. Chem.

56

963-969

2013

-

1

-

1

-

4

-

1

-

1

-

1

-

1

-

1

-

730287

Moniot

Crystal structure analysis of ...

Homo sapiens

J. Struct. Biol.

182

136-143

2013

-

1

-

2

-

1

-

1

-

1

-

1

-

749528

Whitaker

Increased expression of Droso ...

Drosophila melanogaster

Aging

5

682-691

2013

-

1

-

2

-

1

-

1

-

1

-

1

-

1

-

1

-

750413

Buscaino

Distinct roles for Sir2 and R ...

Schizosaccharomyces pombe

EMBO J.

32

1250-1264

2013

-

1

-

1

-

1

-

1

-

1

-

1

-

728857

Maurer

Inhibitors of the NAD(+)-depen ...

Homo sapiens

ACS Med. Chem. Lett.

3

1050-1053

2012

-

22

-

3

-

3

-

32

-

32

62

-

3

-

729982

Yu

SIRT3 protein deacetylates iso ...

Mus musculus

J. Biol. Chem.

287

14078-14086

2012

-

1

-

2

-

2

-

1

-

2

-

1

-

730706

Fischer

Sirt5 deacylation activities s ...

Homo sapiens

PLoS One

7

e45098

2012

-

1

-

1

-

2

-

1

-

1

-

1

-

1

-

1

-

1

-

1

-

1

-

1

-

1

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730713

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A molecular mechanism for dire ...

Homo sapiens

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1

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2

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1

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730947

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Plasmodium falciparum Sir2A p ...

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1

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4

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2

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1

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1

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5

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4

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1

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1

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4

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1

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1

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5

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4

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750907

Dancy

Azalysine analogues as probes ...

Thermotoga maritima

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5138-5148

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1

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2

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3

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1

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1

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2

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1

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1

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2

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3

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1

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5

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2

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718508

Holbourn

Cloning, purification, crystal ...

Homo sapiens

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461-463

2011

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1

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1

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1

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730103

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SIRT1 and SIRT5 activity expre ...

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112

3755-3761

2011

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1

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2

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1

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729970

Ponugoti

SIRT1 deacetylates and inhibit ...

Mus musculus

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285

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2010

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1

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3

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750905

Cen

Transition state of ADP-ribos ...

Archaeoglobus fulgidus

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1

-

3

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3

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4

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1

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1

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1

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3

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4

-

729561

Asher

SIRT1 regulates circadian cloc ...

Homo sapiens

Cell

134

317-328

2008

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1

-

1

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2

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1

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2

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730205

Schlicker

Substrates and regulation mech ...

Homo sapiens

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1

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2

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2

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2

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1

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2

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1

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5

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1

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749886

French

Plasmodium falciparum Sir2 is ...

Plasmodium falciparum

Biochemistry

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2008

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1

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2

3

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2

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1

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3

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3

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1

2

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1

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2

3

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1

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3

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3

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750904

Hu

Highly dissociative and conce ...

Thermotoga maritima, Thermotoga maritima ATCC 43589

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16721-16728

2008

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1

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6

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2

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6

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1

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1

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1

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6

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6

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729683

Jeong

SIRT1 promotes DNA repair acti ...

Homo sapiens

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8-13

2007

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1

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2

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2

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1

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2

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1

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730388

Li

SIRT1 deacetylates and positiv ...

Homo sapiens

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28

91-106

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1

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2

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3

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1

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3

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749884

Smith

Mechanism-based inhibition of ...

Homo sapiens, Saccharomyces cerevisiae

Biochemistry

46

14478-14486

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8

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2

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2

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2

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4

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2

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4

8

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2

-

751549

Sanders

Structural basis for nicotina ...

Saccharomyces cerevisiae

Mol. Cell

25

463-472

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1

9

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1

4

-

1

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2

-

1

-

1

9

-

1

-

4

-

2

-

729802

Vaquero

SirT2 is a histone deacetylase ...

Homo sapiens

Genes Dev.

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1256-1261

2006

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2

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1

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3

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1

-

4

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2

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1

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1

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4

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1

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749880

Smith

Sir2 protein deacetylases evi ...

Saccharomyces cerevisiae

Biochemistry

45

272-282

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1

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3

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1

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5

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1

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1

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Marsh

Sir2 and the acetyltransferas ...

Saccharolobus solfataricus, Saccharolobus solfataricus P2

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2

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751017

Khan

Unstructured conformations ar ...

Saccharomyces cerevisiae

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2

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1

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1

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8

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1

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1

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2

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1

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8

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730962

Cohen

Calorie restriction promotes m ...

Homo sapiens, Rattus norvegicus

Science

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390-392

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Sauve

SIR2 the biochemical mechanis ...

Saccharomyces cerevisiae

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807-826

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1

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3

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2

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1

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5

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1

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750703

North

Sirtuins Sir2-related NAD-dep ...

Archaeoglobus fulgidus, Archaeoglobus fulgidus ATCC 49558, Homo sapiens, Saccharomyces cerevisiae

Genome Biol.

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2004

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3

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4

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7

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5

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3

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3

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3

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5

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1

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Zhao

Structure and substrate bindi ...

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1

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3

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1

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1

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1

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1

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3

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751547

Avalos

Structural basis for the mech ...

Archaeoglobus fulgidus

Mol. Cell

13

639-648

2004

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1

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1

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1

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1

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1

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1

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1

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1

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1

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1

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749878

Sauve

Sir2 regulation by nicotinami ...

Archaeoglobus fulgidus, Mus musculus, Saccharomyces cerevisiae

Biochemistry

42

9249-9256

2003

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15

9

-

12

-

3

-

18

-

3

-

3

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15

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9

-

12

-

18

-

751013

Jackson

Mechanism of nicotinamide inh ...

Homo sapiens, Saccharomyces cerevisiae

J. Biol. Chem.

278

50985-50998

2003

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13

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2

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2

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6

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2

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2

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13

2

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2

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6

-

752023

Parsons

Histone deacetylation by Sir2 ...

Drosophila melanogaster

Proc. Natl. Acad. Sci. USA

100

1609-1614

2003

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1

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1

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1

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3

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1

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11

1

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1

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1

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1

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1

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1

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11

1

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1

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729638

Langley

Human SIR2 deacetylates p53 an ...

Homo sapiens

EMBO J.

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2383-2396

2002

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2

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1

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4

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2

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2

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2

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730840

Onyango

SIRT3, a human SIR2 homologue, ...

Homo sapiens

Proc. Natl. Acad. Sci. USA

99

13653-13658

2002

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1

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2

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1

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3

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1

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1

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2

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1

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1

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752253

Starai

Sir2-dependent activation of ...

Salmonella enterica

Science

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2390-2392

2002

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1

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1

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1

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1

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1

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1

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1

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729560

Vaziri

hSIR2(SIRT1) functions as an N ...

Homo sapiens

Cell

107

149-159

2001

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1

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1

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2

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1

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2

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1

-

749874

Sauve

Chemistry of gene silencing t ...

Thermotoga maritima

Biochemistry

40

15456-15463

2001

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1

-

1

-

1

-

1

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1

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750253

Min

Crystal structure of a SIR2 h ...

Archaeoglobus fulgidus

Cell

105

269-279

2001

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1

4

-

1

-

1

-

1

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1

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1

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2

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1

-

1

4

-

1

-

1

-

1

-

1

-

2

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752068

Landry

The silencing protein SIR2 an ...

Saccharomyces cerevisiae

Proc. Natl. Acad. Sci. USA

97

5807-5811

2000

-

1

-

1

-

2

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1

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2

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1

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1

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1

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1

-

2

-

Activation of the protein deacetylase SIRT6 by long-chain fatty acids and widespread deacylation by mammalian sirtuins

Data extracted from this reference: