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Literature summary for 2.3.1.28 extracted from

  • Goodale, A.; Michailidis, F.; Watts, R.; Chok, S.C.; Hayes, F.
    Characterization of permissive and non-permissive peptide insertion sites in chloramphenicol acetyltransferase (2020), Microb. Pathog., 149, 104395.
    View publication on PubMed

Organism

Organism UniProt Comment Textmining
Escherichia coli P62577
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-

Synonyms

Synonyms Comment Organism
chloramphenicol acetyltransferase
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Escherichia coli

General Information

General Information Comment Organism
additional information pentapeptide insertion mutagenesis is used to identify regions of CATI that are tolerant or intolerant of peptide insertions. The latter pinpoints regions that may be suitable for the design of ligands that block CATI function, whereas the former reveals sites in which peptides or entire proteins may be introduced for the design of bifunctional CATI enzymes Escherichia coli