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Literature summary for 2.3.1.271 extracted from

  • Nishimura, A.; Nasuno, R.; Takagi, H.
    The proline metabolism intermediate DELTA1-pyrroline-5-carboxylate directly inhibits the mitochondrial respiration in budding yeast (2012), FEBS Lett., 586, 2411-2416 .
    View publication on PubMed
Search for more literature for 2.3.1.271

Organism

Organism UniProt Comment Textmining
Saccharomyces cerevisiae E9P8D2
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Saccharomyces cerevisiae Sigma 1278b E9P8D2
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-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
acetyl-CoA + DELTA1-pyrroline-5-carboxylate + H2O
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 Saccharomyces cerevisiae CoA + N-acetyl-glutamate-gamma-semialdehyde
-
 ?
acetyl-CoA + DELTA1-pyrroline-5-carboxylate + H2O
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 Saccharomyces cerevisiae Sigma 1278b CoA + N-acetyl-glutamate-gamma-semialdehyde
-
 ?
acetyl-CoA + L-azetidine-2-carboxylic acid
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 Saccharomyces cerevisiae CoA + N-acetyl-L-azetidine-2-carboxylic acid
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 ?
acetyl-CoA + L-azetidine-2-carboxylic acid
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 Saccharomyces cerevisiae Sigma 1278b CoA + N-acetyl-L-azetidine-2-carboxylic acid
-
 ?

Synonyms

Synonyms Comment Organism
MPR1
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 Saccharomyces cerevisiae

General Information

General Information Comment Organism
metabolism Mpr1 is an antioxidant enzyme that acetylates toxic DELTA1-pyrroline-5-carboxylate involved in reactive oxygen species generation Saccharomyces cerevisiae