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Literature summary for 2.3.1.26 extracted from

  • Hans, C.P.; Zerfaoui, M.; Naura, A.S.; Catling, A.; Boulares, A.H.
    Differential effects of PARP inhibition on vascular cell survival and ACAT-1 expression favouring atherosclerotic plaque stability (2008), Cardiovasc. Res., 78, 429-439.
    View publication on PubMed
Search for more literature for 2.3.1.26

Inhibitors

Inhibitors Comment Organism Structure
additional information poly(ADP-ribose) polymerase inhibition in foam cells resulted in significant sensitization to 7-ketocholesterol by increasing cellular-toxic-free cholesterol, potentially through a down-regulation of ACAT-1 expression Mus musculus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
acyl-CoA + cholesterol Mus musculus
-
 CoA + cholesterol ester
-
 ?

Organism

Organism UniProt Comment Textmining
Mus musculus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
endothelial cell
-
 Mus musculus
-
foam cell
-
 Mus musculus
-
smooth muscle cell
-
 Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
acyl-CoA + cholesterol
-
 Mus musculus CoA + cholesterol ester
-
 ?

Synonyms

Synonyms Comment Organism
ACAT-1
-
 Mus musculus