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Literature summary for 2.3.1.26 extracted from

  • Kitamura, A.; Imai, S.; Yabuki, M.; Komuro, S.
    The new acyl-CoA cholesterol acyltransferase inhibitor SMP-797 does not interact with statins via OATP1B1 in human cryopreserved hepatocytes and oocytes expressing systems (2007), Biopharm. Drug Dispos., 28, 517-525.
    View publication on PubMed

Inhibitors

Inhibitors Comment Organism Structure
N-(4-amino-2, 6-diisopropylphenyl)-N'-[1-butyl-4-[3-(3-hydroxypropoxy) phenyl]-2-oxo-1,2-dihydro-1,8-naphthyridin-3-yl] urea hydrochloride monohydrate SMP-797 Homo sapiens

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
acyl-CoA + cholesterol Homo sapiens
-
CoA + cholesterol ester
-
?

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
hepatocyte
-
Homo sapiens
-
liver
-
Homo sapiens
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
acyl-CoA + cholesterol
-
Homo sapiens CoA + cholesterol ester
-
?

Synonyms

Synonyms Comment Organism
acyl-CoA cholesterol acyltransferase
-
Homo sapiens
acyl-coenzymeA cholesterol acyltransferase
-
Homo sapiens