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Literature summary for 2.3.1.26 extracted from

  • Temel, R.E.; Gebre, A.K.; Parks, J.S.; Rudel, L.L.
    Compared with acyl-CoA:cholesterol O-acyltransferase (ACAT) 1 and lecithin:cholesterol acyltransferase, ACAT2 displays the greatest capacity to differentiate cholesterol from sitosterol (2003), J. Biol. Chem., 278, 47594-47601.
    View publication on PubMed

Organism

Organism UniProt Comment Textmining
Chlorocebus aethiops
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recombinant isoforms ACAT1 and ACAT2
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information isoform ACAT2 displays significantly greater selectivity for cholesterol compared with sitosterol than ACAT1 Chlorocebus aethiops ?
-
?
oleoyl-CoA + cholesterol
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Chlorocebus aethiops CoA + cholesteryl oleate
-
?
oleoyl-CoA + sitosterol
-
Chlorocebus aethiops CoA + sitosteryl oleate
-
?