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Literature summary for 2.3.1.255 extracted from

  • Gong, X.; Boyer, J.B.; Gierlich, S.; Pozoga, M.; Weidenhausen, J.; Sinning, I.; Meinnel, T.; Giglione, C.; Wang, Y.; Hell, R.; Wirtz, M.
    HYPK controls stability and catalytic activity of the N-terminal acetyltransferase A in Arabidopsis thaliana (2024), Cell Rep., 43, 113768.
    View publication on PubMed
Search for more literature for 2.3.1.255

Organism

Organism UniProt Comment Textmining
Arabidopsis thaliana Q8VZM1 and Q9FKI4 auxiliary subunit NAA15, Q9FKI4i.e. catalytic subunit NAA10
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Source Tissue

Source Tissue Comment Organism Textmining
leaf HYPK stabilizes the core NatA specifically in the leaves of plants Arabidopsis thaliana
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Synonyms

Synonyms Comment Organism
AA15
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 Arabidopsis thaliana
At1g80410
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 Arabidopsis thaliana
At5g13780
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 Arabidopsis thaliana
NAA10
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 Arabidopsis thaliana

General Information

General Information Comment Organism
physiological function in Arabidopsis thaliana, the UBA domain of Huntingtin yeast partner K (HYPK) is vital for stabilizing the NatA complex in an organ-specific manner. The N terminus of HYPK, including helix alpha1, is critical for promoting NatA activity on substrates starting with various amino acids. Deleting 42 amino acids inside the HYPK N terminus causes substantial destabilization of the plant proteome and higher tolerance toward drought stress Arabidopsis thaliana