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Literature summary for 2.3.1.243 extracted from

  • Taniguchi, C.; Sugawara, T.; Onoue, S.; Kawahara, K.
    Structural modification of Escherichia coli lipid A by myristoyltransferase gene from Klebsiella pneumoniae (2019), Microbiol. Immunol., 63, 334-337 .
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
lipid A in lipopolysaccharide (LPS) of Escherichia coli mutant strains is modified by the introduction of myristoyltransferase gene cloned from Klebsiella pneumoniae. When the lpxL2 gene is introduced into the mutant having lipid A containing only 3-hydroxymyristic acids, it produces lipid A with two additional myristic acids (C14:0). When the same gene is introduced into the mutant with pentaacylated lipid A containing one lauric acid (C12:0), C12:0 is replaced by C14:0 Klebsiella pneumoniae

Organism

Organism UniProt Comment Textmining
Klebsiella pneumoniae
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Klebsiella pneumoniae NBRC 14940T
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information lipid A in lipopolysaccharide of Escherichia coli mutant strains is modified by the introduction of myristoyltransferase gene cloned from Klebsiella pneumoniae. When the lpxL2 gene is introduced into the mutant having lipid A containing only 3-hydroxymyristic acids, it produces lipid A with two additional myristic acids (C14:0). When the same gene is introduced into the mutant with pentaacylated lipid A containing one lauric acid (C12:0), C12:0 is replaced by C14:0 Klebsiella pneumoniae ?
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-
additional information lipid A in lipopolysaccharide of Escherichia coli mutant strains is modified by the introduction of myristoyltransferase gene cloned from Klebsiella pneumoniae. When the lpxL2 gene is introduced into the mutant having lipid A containing only 3-hydroxymyristic acids, it produces lipid A with two additional myristic acids (C14:0). When the same gene is introduced into the mutant with pentaacylated lipid A containing one lauric acid (C12:0), C12:0 is replaced by C14:0 Klebsiella pneumoniae NBRC 14940T ?
-
-

Synonyms

Synonyms Comment Organism
LpxL2
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Klebsiella pneumoniae