Literature summary for 2.3.1.243 extracted from

Erova, T.; Kirtley, M.; Fitts, E.; Ponnusamy, D.; Baze, W.; Andersson, J.; Cong, Y.; Tiner, B.; Sha, J.; Chopra, A.
Protective immunity elicited by oral immunization of mice with Salmonella enterica serovar typhimurium braun lipoprotein (Lpp) and acetyltransferase (MsbB) mutants (2016), Front. Cell. Infect. Microbiol., 6, 148 .

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Application

Application	Comment	Organism
drug development	mutants deleted either for the Braun lipoprotein genes lppA and lppB or in combination with the msbB gene, which encodes an acetyltransferase required for lipid A modification of lipopolysaccharide provided complete protection to immunized mice against a lethal oral challenge dose of wild type Salmonella typhimurium. These mutants may serve as excellent vaccine candidates and also provide a platform for delivering heterologous antigens	Salmonella enterica subsp. enterica serovar Typhimurium

Organism

Organism	UniProt	Comment	Textmining
Salmonella enterica subsp. enterica serovar Typhimurium	A0A0F6B2L6	-	-
Salmonella enterica subsp. enterica serovar Typhimurium 14028s	A0A0F6B2L6	-	-

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Release 2023.1 (January 2023)