Literature summary for 2.3.1.24 extracted from

Erez-Roman, R.; Pienik, R.; Futerman, A.H.
Increased ceramide synthase 2 and 6 mRNA levels in breast cancer tissues and correlation with sphingosine kinase expression (2010), Biochem. Biophys. Res. Commun., 391, 219-223 .

Search for more literature for 2.3.1.24

Application

Application	Comment	Organism
diagnostics	important role for the CerS genes in breast cancer etiology or diagnosis, overview	Homo sapiens

Cloned(Commentary)

Cloned (Comment)	Organism
gene CERS4, isozyme expression analysis	Homo sapiens
gene CERS6, isozyme expression analysis	Homo sapiens

Organism

Organism	UniProt	Comment	Textmining
Homo sapiens	Q6ZMG9	-	-
Homo sapiens	Q9HA82	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
breast cancer cell	isozymes CerS2 (EC 2.3.1.297) and CerS6 (EC 2.3.1.24) mRNA is significantly elevated in breast cancer tissue compared to normal tissue, with approximately half of the individuals showing elevated CerS2 and CerS6 mRNA. A significant correlation is found between CerS2 and CerS6 isozyme expression, and between isozymes CerS4 (EC 2.3.1.24) and CerS2/CerS6 expression	Homo sapiens	-

Synonyms

Synonyms	Comment	Organism
ceramide synthase 4	-	Homo sapiens
ceramide synthase 6	-	Homo sapiens
CerS4	-	Homo sapiens
CerS6	-	Homo sapiens

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Release 2023.1 (January 2023)