Literature summary for 2.3.1.232 extracted from

Lee, H.L.; Kim, S.Y.; Kim, E.J.; Han, D.Y.; Kim, B.G.; Ahn, J.H.
Synthesis of methylated anthranilate derivatives using engineered strains of Escherichia coli (2019), J. Microbiol. Biotechnol., 29, 839-844 .

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Application

Application	Comment	Organism
synthesis	three anthranilate derivatives, N-methylanthranilate, methyl anthranilate, and methyl N-methylanthranilate are synthesized using metabolically engineered stains of Escherichia coli. NMT encoding N-methyltransferase from Ruta graveolens, AMAT encoding anthraniloyl-coenzyme A (CoA):methanol acyltransferase from Vitis labrusca, and pqsA encoding anthranilate coenzyme A ligase from Pseudomonas aeruginosa are cloned and Eschetrichia coli strains harboring these genes were used to synthesize the three desired compounds. Escherichia coli mutants (metJ, trpD, tyrR mutants), which provide more anthranilate and/or S-adenosyl methionine, are used to increase the production of the synthesized compounds. 0.1853 mM N-methylanthranilate and 0.0952 mM methyl N-methylanthranilate are synthesized	Vitis labrusca

Organism

Organism	UniProt	Comment	Textmining
Vitis labrusca	Q3ZPN4	-	-

Synonyms

Synonyms	Comment	Organism
AMAT	-	Vitis labrusca
anthraniloyl-coenzyme A:methanol acyltransferase	-	Vitis labrusca

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Release 2023.1 (January 2023)