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Literature summary for 2.3.1.231 extracted from

  • Noma, A.; Kirino, Y.; Ikeuchi, Y.; Suzuki, T.
    Biosynthesis of wybutosine, a hyper-modified nucleoside in eukaryotic phenylalanine tRNA (2006), EMBO J., 25, 2142-2154.
    View publication on PubMedView publication on EuropePMC

Organism

Organism UniProt Comment Textmining
Saccharomyces cerevisiae
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-
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Saccharomyces cerevisiae BY4742
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-
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Purification (Commentary)

Purification (Comment) Organism
Ni2+-chelating column chromatography Saccharomyces cerevisiae

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
S-adenosyl-L-methionine + 7-[(3S)-3-amino-3-(methoxycarbonyl)propyl]wyosine-187 in tRNAPhe + CO2
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Saccharomyces cerevisiae S-adenosyl-L-homocysteine + wybutosine-187 in tRNAPhe
-
?
S-adenosyl-L-methionine + 7-[(3S)-3-amino-3-(methoxycarbonyl)propyl]wyosine-187 in tRNAPhe + CO2
-
Saccharomyces cerevisiae BY4742 S-adenosyl-L-homocysteine + wybutosine-187 in tRNAPhe
-
?
S-adenosyl-L-methionine + 7-[(3S)-3-amino-3-carboxypropyl]wyosine72 in tRNAPhe the enzyme catalyzes methylation of the carboxyl group of the methionine moiety in wybutosine-72 to convert it to wybutosine-58 Saccharomyces cerevisiae S-adenosyl-L-homocysteine + wybutosine-72 in tRNAPhe
-
?
S-adenosyl-L-methionine + 7-[(3S)-3-amino-3-carboxypropyl]wyosine72 in tRNAPhe the enzyme catalyzes methylation of the carboxyl group of the methionine moiety in wybutosine-72 to convert it to wybutosine-58 Saccharomyces cerevisiae BY4742 S-adenosyl-L-homocysteine + wybutosine-72 in tRNAPhe
-
?

Synonyms

Synonyms Comment Organism
tRNA-yW synthesizing enzyme 4
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Saccharomyces cerevisiae
TYW4
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Saccharomyces cerevisiae

Cofactor

Cofactor Comment Organism Structure
S-adenosyl-L-methionine
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Saccharomyces cerevisiae