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Literature summary for 2.3.1.23 extracted from
- Inhibition of a Golgi complex lysophospholipid acyltransferase induces membrane tubule formation and retrograde trafficking (2003), Mol. Biol. Cell, 14, 3459-3469.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| 2,2-dimethyl-N-(2,4,6-trimethoxyphenyl)dodecanamide | - |
Rattus norvegicus |  |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| Golgi membrane | Golgi membrane tubule formation can result from increasing the content of lysophospholipids in membranes, either by stimulation of a phospholipase A2 or by inhibition of an lysophosphatidylcholine acyltransferase. The two opposing enzyme activities may help to coordinately regulate Golgi membrane shape and tubule formation | Rattus norvegicus | 139 | - |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | Rattus norvegicus | Golgi membrane tubule formation can result from increasing the content of lysophospholipids in membranes, either by stimulation of a phospholipase A2 or by inhibition of an lysophosphatidylcholine acyltransferase. The two opposing enzyme activities may help to coordinately regulate Golgi membrane shape and tubule formation | ? | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rattus norvegicus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| liver | - |
Rattus norvegicus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | Golgi membrane tubule formation can result from increasing the content of lysophospholipids in membranes, either by stimulation of a phospholipase A2 or by inhibition of an lysophosphatidylcholine acyltransferase. The two opposing enzyme activities may help to coordinately regulate Golgi membrane shape and tubule formation | Rattus norvegicus | ? | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| LPAT | - |
Rattus norvegicus |
| lysophosphatidylcholine acyltransferase | - |
Rattus norvegicus |
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Release 2023.1 (January 2023)
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