Literature summary for 2.3.1.226 extracted from

McGowan, S.J.; Sebaihia, M.; Porter, L.E.; Stewart, G.S.; Williams, P.; Bycroft, B.W.; Salmond, G.P.
Analysis of bacterial carbapenem antibiotic production genes reveals a novel beta-lactam biosynthesis pathway (1996), Mol. Microbiol., 22, 415-426.

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Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
malonyl-CoA + (S)-1-pyrroline-5-carboxylate + H2O	Pectobacterium carotovorum	-	CoA + (2S,5S)-5-carboxymethylproline + CO2	-	?
malonyl-CoA + (S)-1-pyrroline-5-carboxylate + H2O	Pectobacterium carotovorum GS101	-	CoA + (2S,5S)-5-carboxymethylproline + CO2	-	?

Organism

Organism	UniProt	Comment	Textmining
Pectobacterium carotovorum	-	-	-
Pectobacterium carotovorum GS101	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
malonyl-CoA + (S)-1-pyrroline-5-carboxylate + H2O	-	Pectobacterium carotovorum	CoA + (2S,5S)-5-carboxymethylproline + CO2	-	?
malonyl-CoA + (S)-1-pyrroline-5-carboxylate + H2O	-	Pectobacterium carotovorum GS101	CoA + (2S,5S)-5-carboxymethylproline + CO2	-	?

Synonyms

Synonyms	Comment	Organism
CarB	-	Pectobacterium carotovorum

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Release 2023.1 (January 2023)