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Literature summary for 2.3.1.218 extracted from
- A combinatorial approach to optimize the production of curcuminoids from tyrosine in Escherichia coli (2020), Front. Bioeng. Biotechnol., 8, 59 .
Application
| Application | Comment | Organism |
|---|---|---|
| synthesis | design, construction and optimization of a heterologous pathway to produce curcuminoids in Escherichia coli. This pathway involves six enzymes, tyrosine ammonia lyase (TAL), 4-coumarate 3-hydroxylase (C3H), caffeic acid O-methyltransferase (COMT), 4-coumarate-CoA ligase (4CL), diketide-CoA synthase (DCS), and curcumin synthase (CURS1). Curcumin production is enhanced and reachs 43.2 mM, corresponding to an improvement of 160% comparing to mono-culture system | Curcuma longa |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Curcuma longa | C0SVZ5 | - |
- |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| DCS | - |
Curcuma longa |
| diketide-CoA synthase | - |
Curcuma longa |
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Release 2023.1 (January 2023)
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